Principles

Johannes G. Filser; Jeroen T.M. Buters; Leslie Schwarz; John B. Watkins; Lesley Stanley; Jens Schlossmann; Franz Hofmann; Victor J. Feron; Diana Jonker; Thomas Efferth; Bernd Kaina; Horst Spielmann; Peter Calow; Valery E. Forbes

doi:10.1002/9780470868959.ch2

Principles

Johannes G. Filser
, Jeroen T.M. Buters
, Leslie Schwarz
, John B. Watkins
, Lesley Stanley
, Jens Schlossmann
, Franz Hofmann
, Victor J. Feron
, Diana Jonker
, Thomas Efferth
, Bernd Kaina
, Horst Spielmann
, Peter Calow
, Valery E. Forbes

Chair of Molecular allergology and Environment

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Scopus citations

Abstract

The object of toxicokinetics is the investigation of absorption, distribution, and elimination of toxicants and their toxicologically relevant metabolites as functions of dose and time.

Original language	English
Title of host publication	Toxicology and Risk Assessment
Subtitle of host publication	A Comprehensive Introduction
Publisher	John Wiley & Sons, Ltd
Pages	19-203
Number of pages	185
ISBN (Print)	9780470868935
DOIs	https://doi.org/10.1002/9780470868959.ch2
State	Published - 8 Feb 2008

Keywords

Anion-transport systems
Cancer-linked disease
Enzyme-mediated substance conversion
Intravascular thrombus formation
Isoenzymes exhibiting different substrate specificities
Messenger ribonucleic acid (mRNA)
Morphologically and functionally differing entities
One-compartment model saturation kinetics
Richly perfused organs
Toxic potential and (estimated) exposure

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10.1002/9780470868959.ch2

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title = "Principles",

abstract = "The object of toxicokinetics is the investigation of absorption, distribution, and elimination of toxicants and their toxicologically relevant metabolites as functions of dose and time.",

keywords = "Anion-transport systems, Cancer-linked disease, Enzyme-mediated substance conversion, Intravascular thrombus formation, Isoenzymes exhibiting different substrate specificities, Messenger ribonucleic acid (mRNA), Morphologically and functionally differing entities, One-compartment model saturation kinetics, Richly perfused organs, Toxic potential and (estimated) exposure",

author = "Filser, \{Johannes G.\} and Buters, \{Jeroen T.M.\} and Leslie Schwarz and Watkins, \{John B.\} and Lesley Stanley and Jens Schlossmann and Franz Hofmann and Feron, \{Victor J.\} and Diana Jonker and Thomas Efferth and Bernd Kaina and Horst Spielmann and Peter Calow and Forbes, \{Valery E.\}",

year = "2008",

month = feb,

day = "8",

doi = "10.1002/9780470868959.ch2",

language = "English",

isbn = "9780470868935",

pages = "19--203",

booktitle = "Toxicology and Risk Assessment",

publisher = "John Wiley \& Sons, Ltd",

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TY - CHAP

T1 - Principles

AU - Filser, Johannes G.

AU - Buters, Jeroen T.M.

AU - Schwarz, Leslie

AU - Watkins, John B.

AU - Stanley, Lesley

AU - Schlossmann, Jens

AU - Hofmann, Franz

AU - Feron, Victor J.

AU - Jonker, Diana

AU - Efferth, Thomas

AU - Kaina, Bernd

AU - Spielmann, Horst

AU - Calow, Peter

AU - Forbes, Valery E.

PY - 2008/2/8

Y1 - 2008/2/8

N2 - The object of toxicokinetics is the investigation of absorption, distribution, and elimination of toxicants and their toxicologically relevant metabolites as functions of dose and time.

AB - The object of toxicokinetics is the investigation of absorption, distribution, and elimination of toxicants and their toxicologically relevant metabolites as functions of dose and time.

KW - Anion-transport systems

KW - Cancer-linked disease

KW - Enzyme-mediated substance conversion

KW - Intravascular thrombus formation

KW - Isoenzymes exhibiting different substrate specificities

KW - Messenger ribonucleic acid (mRNA)

KW - Morphologically and functionally differing entities

KW - One-compartment model saturation kinetics

KW - Richly perfused organs

KW - Toxic potential and (estimated) exposure

UR - https://www.scopus.com/pages/publications/84889492924

U2 - 10.1002/9780470868959.ch2

DO - 10.1002/9780470868959.ch2

M3 - Chapter

AN - SCOPUS:84889492924

SN - 9780470868935

SP - 19

EP - 203

BT - Toxicology and Risk Assessment

PB - John Wiley & Sons, Ltd

ER -

Principles

Abstract

Keywords

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