Prevention of Cervical Cancer

Peter Hillemanns; Klaus Friese; Christian Dannecker; Stefanie Klug; Ulrike Seifert; Thomas Iftner; Juliane Hädicke; Thomas Löning; Lars Horn; Dietmar Schmidt; Hans Ikenberg; Manfred Steiner; Ulrich Freitag; Uwe Siebert; Gaby Sroczynski; Willi Sauerbrei; Matthias W. Beckmann; Marion Gebhardt; Michael Friedrich; Karsten Münstedt; Achim Schneider; Andreas Kaufmann; K. Ulrich Petry; Axel P.A. Schäfer; Michael Pawlita; Joachim Weis; Anja Mehnert; Mathias Fehr; Christoph Grimm; Olaf Reich; Marc Arbyn; Jos Kleijnen; Simone Wesselmann; Monika Nothacker; Markus Follmann; Thomas Langer; Matthias Jentschke

doi:10.1055/a-0818-5440

Prevention of Cervical Cancer

Peter Hillemanns, Klaus Friese, Christian Dannecker, Stefanie Klug, Ulrike Seifert, Thomas Iftner, Juliane Hädicke, Thomas Löning, Lars Horn, Dietmar Schmidt, Hans Ikenberg, Manfred Steiner, Ulrich Freitag, Uwe Siebert, Gaby Sroczynski, Willi Sauerbrei, Matthias W. Beckmann, Marion Gebhardt, Michael Friedrich, Karsten MünstedtAchim Schneider, Andreas Kaufmann, K. Ulrich Petry, Axel P.A. Schäfer, Michael Pawlita, Joachim Weis, Anja Mehnert, Mathias Fehr, Christoph Grimm, Olaf Reich, Marc Arbyn, Jos Kleijnen, Simone Wesselmann, Monika Nothacker, Markus Follmann, Thomas Langer, Matthias Jentschke

Chair of Epidemiology

Research output: Contribution to journal › Review article › peer-review

22 Scopus citations

Abstract

Aims Annual opportunistic screening for cervical carcinoma has been carried out in Germany since 1971. The creation of this S3 guideline meets an important need, outlined in the National Cancer Plan, with regard to screening for cervical cancer, as the guideline aims to provide important information and support for planned organized screening for cervical cancer in Germany. Methods With the financial support of German Cancer Aid, 21 professional societies developed evidence-based statements and recommendations (classified using the GRADE system) for the screening, management and treatment of precancerous conditions of the cervix. Two independent scientific institutes compiled systematic reviews for this guideline. Recommendations The first part of this short summary presents the pathological basis and considers various questions related to screening for cervical cancer. As also reported in earlier reviews, the meta-analysis by Kleijnen Systematic Reviews showed that HPV-based screening offers better protection against invasive cervical cancer compared to cytology-based screening. The authors of this guideline therefore recommend - in accordance with the guideline of the Joint National Committee of Germany (Gemeinsamer Bundesauschuss, G-BA) - that women aged 35 and above should be examined at regular intervals (at least every 3 years) and undergo HPV-based screening. Co-testing can also be carried out. Women between the ages of 20 and 35 should have cytological screening every 2 years.

Original language	English
Pages (from-to)	148-158
Number of pages	11
Journal	Geburtshilfe und Frauenheilkunde
Volume	79
Issue number	2
DOIs	https://doi.org/10.1055/a-0818-5440
State	Published - 2019

Keywords

HPV
cervical cancer
cervical intraepithelial neoplasia (CIN)
cervical precancerous condition

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1055/a-0818-5440

Cite this

Hillemanns, P., Friese, K., Dannecker, C., Klug, S., Seifert, U., Iftner, T., Hädicke, J., Löning, T., Horn, L., Schmidt, D., Ikenberg, H., Steiner, M., Freitag, U., Siebert, U., Sroczynski, G., Sauerbrei, W., Beckmann, M. W., Gebhardt, M., Friedrich, M., ... Jentschke, M. (2019). Prevention of Cervical Cancer. Geburtshilfe und Frauenheilkunde, 79(2), 148-158. https://doi.org/10.1055/a-0818-5440

@article{c4fa9e2af8864c6380c765408cc54583,

title = "Prevention of Cervical Cancer",

abstract = "Aims Annual opportunistic screening for cervical carcinoma has been carried out in Germany since 1971. The creation of this S3 guideline meets an important need, outlined in the National Cancer Plan, with regard to screening for cervical cancer, as the guideline aims to provide important information and support for planned organized screening for cervical cancer in Germany. Methods With the financial support of German Cancer Aid, 21 professional societies developed evidence-based statements and recommendations (classified using the GRADE system) for the screening, management and treatment of precancerous conditions of the cervix. Two independent scientific institutes compiled systematic reviews for this guideline. Recommendations The first part of this short summary presents the pathological basis and considers various questions related to screening for cervical cancer. As also reported in earlier reviews, the meta-analysis by Kleijnen Systematic Reviews showed that HPV-based screening offers better protection against invasive cervical cancer compared to cytology-based screening. The authors of this guideline therefore recommend - in accordance with the guideline of the Joint National Committee of Germany (Gemeinsamer Bundesauschuss, G-BA) - that women aged 35 and above should be examined at regular intervals (at least every 3 years) and undergo HPV-based screening. Co-testing can also be carried out. Women between the ages of 20 and 35 should have cytological screening every 2 years.",

keywords = "HPV, cervical cancer, cervical intraepithelial neoplasia (CIN), cervical precancerous condition",

author = "Peter Hillemanns and Klaus Friese and Christian Dannecker and Stefanie Klug and Ulrike Seifert and Thomas Iftner and Juliane H{\"a}dicke and Thomas L{\"o}ning and Lars Horn and Dietmar Schmidt and Hans Ikenberg and Manfred Steiner and Ulrich Freitag and Uwe Siebert and Gaby Sroczynski and Willi Sauerbrei and Beckmann, {Matthias W.} and Marion Gebhardt and Michael Friedrich and Karsten M{\"u}nstedt and Achim Schneider and Andreas Kaufmann and Petry, {K. Ulrich} and Sch{\"a}fer, {Axel P.A.} and Michael Pawlita and Joachim Weis and Anja Mehnert and Mathias Fehr and Christoph Grimm and Olaf Reich and Marc Arbyn and Jos Kleijnen and Simone Wesselmann and Monika Nothacker and Markus Follmann and Thomas Langer and Matthias Jentschke",

note = "Publisher Copyright: {\textcopyright} 2019 Georg Thieme Verlag KG Stuttgart New York.",

year = "2019",

doi = "10.1055/a-0818-5440",

language = "English",

volume = "79",

pages = "148--158",

journal = "Geburtshilfe und Frauenheilkunde",

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Hillemanns, P, Friese, K, Dannecker, C, Klug, S, Seifert, U, Iftner, T, Hädicke, J, Löning, T, Horn, L, Schmidt, D, Ikenberg, H, Steiner, M, Freitag, U, Siebert, U, Sroczynski, G, Sauerbrei, W, Beckmann, MW, Gebhardt, M, Friedrich, M, Münstedt, K, Schneider, A, Kaufmann, A, Petry, KU, Schäfer, APA, Pawlita, M, Weis, J, Mehnert, A, Fehr, M, Grimm, C, Reich, O, Arbyn, M, Kleijnen, J, Wesselmann, S, Nothacker, M, Follmann, M, Langer, T & Jentschke, M 2019, 'Prevention of Cervical Cancer', Geburtshilfe und Frauenheilkunde, vol. 79, no. 2, pp. 148-158. https://doi.org/10.1055/a-0818-5440

TY - JOUR

T1 - Prevention of Cervical Cancer

AU - Hillemanns, Peter

AU - Friese, Klaus

AU - Dannecker, Christian

AU - Klug, Stefanie

AU - Seifert, Ulrike

AU - Iftner, Thomas

AU - Hädicke, Juliane

AU - Löning, Thomas

AU - Horn, Lars

AU - Schmidt, Dietmar

AU - Ikenberg, Hans

AU - Steiner, Manfred

AU - Freitag, Ulrich

AU - Siebert, Uwe

AU - Sroczynski, Gaby

AU - Sauerbrei, Willi

AU - Beckmann, Matthias W.

AU - Gebhardt, Marion

AU - Friedrich, Michael

AU - Münstedt, Karsten

AU - Schneider, Achim

AU - Kaufmann, Andreas

AU - Petry, K. Ulrich

AU - Schäfer, Axel P.A.

AU - Pawlita, Michael

AU - Weis, Joachim

AU - Mehnert, Anja

AU - Fehr, Mathias

AU - Grimm, Christoph

AU - Reich, Olaf

AU - Arbyn, Marc

AU - Kleijnen, Jos

AU - Wesselmann, Simone

AU - Nothacker, Monika

AU - Follmann, Markus

AU - Langer, Thomas

AU - Jentschke, Matthias

PY - 2019

Y1 - 2019

N2 - Aims Annual opportunistic screening for cervical carcinoma has been carried out in Germany since 1971. The creation of this S3 guideline meets an important need, outlined in the National Cancer Plan, with regard to screening for cervical cancer, as the guideline aims to provide important information and support for planned organized screening for cervical cancer in Germany. Methods With the financial support of German Cancer Aid, 21 professional societies developed evidence-based statements and recommendations (classified using the GRADE system) for the screening, management and treatment of precancerous conditions of the cervix. Two independent scientific institutes compiled systematic reviews for this guideline. Recommendations The first part of this short summary presents the pathological basis and considers various questions related to screening for cervical cancer. As also reported in earlier reviews, the meta-analysis by Kleijnen Systematic Reviews showed that HPV-based screening offers better protection against invasive cervical cancer compared to cytology-based screening. The authors of this guideline therefore recommend - in accordance with the guideline of the Joint National Committee of Germany (Gemeinsamer Bundesauschuss, G-BA) - that women aged 35 and above should be examined at regular intervals (at least every 3 years) and undergo HPV-based screening. Co-testing can also be carried out. Women between the ages of 20 and 35 should have cytological screening every 2 years.

AB - Aims Annual opportunistic screening for cervical carcinoma has been carried out in Germany since 1971. The creation of this S3 guideline meets an important need, outlined in the National Cancer Plan, with regard to screening for cervical cancer, as the guideline aims to provide important information and support for planned organized screening for cervical cancer in Germany. Methods With the financial support of German Cancer Aid, 21 professional societies developed evidence-based statements and recommendations (classified using the GRADE system) for the screening, management and treatment of precancerous conditions of the cervix. Two independent scientific institutes compiled systematic reviews for this guideline. Recommendations The first part of this short summary presents the pathological basis and considers various questions related to screening for cervical cancer. As also reported in earlier reviews, the meta-analysis by Kleijnen Systematic Reviews showed that HPV-based screening offers better protection against invasive cervical cancer compared to cytology-based screening. The authors of this guideline therefore recommend - in accordance with the guideline of the Joint National Committee of Germany (Gemeinsamer Bundesauschuss, G-BA) - that women aged 35 and above should be examined at regular intervals (at least every 3 years) and undergo HPV-based screening. Co-testing can also be carried out. Women between the ages of 20 and 35 should have cytological screening every 2 years.

KW - HPV

KW - cervical cancer

KW - cervical intraepithelial neoplasia (CIN)

KW - cervical precancerous condition

UR - http://www.scopus.com/inward/record.url?scp=85061920164&partnerID=8YFLogxK

U2 - 10.1055/a-0818-5440

DO - 10.1055/a-0818-5440

M3 - Review article

AN - SCOPUS:85061920164

SN - 0016-5751

VL - 79

SP - 148

EP - 158

JO - Geburtshilfe und Frauenheilkunde

JF - Geburtshilfe und Frauenheilkunde

IS - 2

ER -

Prevention of Cervical Cancer

Abstract

Keywords

UN SDGs

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