Precision oncology – Guideline of the Austrian, German and Swiss Societies for hematology and medical oncology

Damian T. Rieke; Michael Bitzer; Annalen Bleckmann; Alexander Desuki; Thomas Ernst; Irene Esposito; Armin Gerger; Hanno Glimm; Peter Horak; Daniel Hübschmann; Anna Lena Illert; Volker Kunzmann; Sonja Loges; Ina Pretzell; Katja Schmitz; Andreas Seeber; Bärbel Söhlke; Andreas Wicki; Jürgen Wolf; Georg Maschmeyer

doi:10.1016/j.ejca.2025.115331

Precision oncology – Guideline of the Austrian, German and Swiss Societies for hematology and medical oncology

Damian T. Rieke, Michael Bitzer, Annalen Bleckmann, Alexander Desuki, Thomas Ernst, Irene Esposito, Armin Gerger, Hanno Glimm, Peter Horak, Daniel Hübschmann, Anna Lena Illert, Volker Kunzmann, Sonja Loges, Ina Pretzell, Katja Schmitz, Andreas Seeber, Bärbel Söhlke, Andreas Wicki, Jürgen Wolf, Georg Maschmeyer

Associate Professorship of Personalized Oncology

Research output: Contribution to journal › Review article › peer-review

Abstract

Precision oncology is a multi-step process including patient selection, tumor profiling, molecular tumor board discussion and personalized cancer management. So far, it remains largely unstandardized. The implementation of precision oncology can be beneficial for patients but implementation differs widely between tumor types and local practices. A working group was established by the Austrian, German and Swiss societies for Hematology and Medical Oncology to establish an expert consensus on evidence-based standards and implementation of precision oncology. Herein, we present a summary of this guideline. The full documents are available at www.onkopedia-guidelines.info

Original language	English
Article number	115331
Journal	European Journal of Cancer
Volume	220
DOIs	https://doi.org/10.1016/j.ejca.2025.115331
State	Published - 2 May 2025

Keywords

Molecular Oncology
Personalized medicine
Precision Oncology
Targeted therapy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ejca.2025.115331

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Rieke, D. T., Bitzer, M., Bleckmann, A., Desuki, A., Ernst, T., Esposito, I., Gerger, A., Glimm, H., Horak, P., Hübschmann, D., Illert, A. L., Kunzmann, V., Loges, S., Pretzell, I., Schmitz, K., Seeber, A., Söhlke, B., Wicki, A., Wolf, J., & Maschmeyer, G. (2025). Precision oncology – Guideline of the Austrian, German and Swiss Societies for hematology and medical oncology. European Journal of Cancer, 220, Article 115331. https://doi.org/10.1016/j.ejca.2025.115331

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abstract = "Precision oncology is a multi-step process including patient selection, tumor profiling, molecular tumor board discussion and personalized cancer management. So far, it remains largely unstandardized. The implementation of precision oncology can be beneficial for patients but implementation differs widely between tumor types and local practices. A working group was established by the Austrian, German and Swiss societies for Hematology and Medical Oncology to establish an expert consensus on evidence-based standards and implementation of precision oncology. Herein, we present a summary of this guideline. The full documents are available at www.onkopedia-guidelines.info",

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author = "Rieke, {Damian T.} and Michael Bitzer and Annalen Bleckmann and Alexander Desuki and Thomas Ernst and Irene Esposito and Armin Gerger and Hanno Glimm and Peter Horak and Daniel H{\"u}bschmann and Illert, {Anna Lena} and Volker Kunzmann and Sonja Loges and Ina Pretzell and Katja Schmitz and Andreas Seeber and B{\"a}rbel S{\"o}hlke and Andreas Wicki and J{\"u}rgen Wolf and Georg Maschmeyer",

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year = "2025",

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doi = "10.1016/j.ejca.2025.115331",

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Rieke, DT, Bitzer, M, Bleckmann, A, Desuki, A, Ernst, T, Esposito, I, Gerger, A, Glimm, H, Horak, P, Hübschmann, D, Illert, AL, Kunzmann, V, Loges, S, Pretzell, I, Schmitz, K, Seeber, A, Söhlke, B, Wicki, A, Wolf, J & Maschmeyer, G 2025, 'Precision oncology – Guideline of the Austrian, German and Swiss Societies for hematology and medical oncology', European Journal of Cancer, vol. 220, 115331. https://doi.org/10.1016/j.ejca.2025.115331

TY - JOUR

T1 - Precision oncology – Guideline of the Austrian, German and Swiss Societies for hematology and medical oncology

AU - Rieke, Damian T.

AU - Bitzer, Michael

AU - Bleckmann, Annalen

AU - Desuki, Alexander

AU - Ernst, Thomas

AU - Esposito, Irene

AU - Gerger, Armin

AU - Glimm, Hanno

AU - Horak, Peter

AU - Hübschmann, Daniel

AU - Illert, Anna Lena

AU - Kunzmann, Volker

AU - Loges, Sonja

AU - Pretzell, Ina

AU - Schmitz, Katja

AU - Seeber, Andreas

AU - Söhlke, Bärbel

AU - Wicki, Andreas

AU - Wolf, Jürgen

AU - Maschmeyer, Georg

PY - 2025/5/2

Y1 - 2025/5/2

N2 - Precision oncology is a multi-step process including patient selection, tumor profiling, molecular tumor board discussion and personalized cancer management. So far, it remains largely unstandardized. The implementation of precision oncology can be beneficial for patients but implementation differs widely between tumor types and local practices. A working group was established by the Austrian, German and Swiss societies for Hematology and Medical Oncology to establish an expert consensus on evidence-based standards and implementation of precision oncology. Herein, we present a summary of this guideline. The full documents are available at www.onkopedia-guidelines.info

AB - Precision oncology is a multi-step process including patient selection, tumor profiling, molecular tumor board discussion and personalized cancer management. So far, it remains largely unstandardized. The implementation of precision oncology can be beneficial for patients but implementation differs widely between tumor types and local practices. A working group was established by the Austrian, German and Swiss societies for Hematology and Medical Oncology to establish an expert consensus on evidence-based standards and implementation of precision oncology. Herein, we present a summary of this guideline. The full documents are available at www.onkopedia-guidelines.info

KW - Molecular Oncology

KW - Personalized medicine

KW - Precision Oncology

KW - Targeted therapy

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U2 - 10.1016/j.ejca.2025.115331

DO - 10.1016/j.ejca.2025.115331

M3 - Review article

AN - SCOPUS:86000334192

SN - 0959-8049

VL - 220

JO - European Journal of Cancer

JF - European Journal of Cancer

M1 - 115331

ER -

Precision oncology – Guideline of the Austrian, German and Swiss Societies for hematology and medical oncology

Abstract

Keywords

UN SDGs

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