Precision Needle Tip Localization Using Optical Coherence Tomography Images for Subretinal Injection

Mingchuan Zhou, Kai Huang, Abouzar Eslami, Hessam Roodaki, Daniel Zapp, Mathias Maier, Chris P. Lohmann, Alois Knoll, M. Ali Nasseri

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

27 Scopus citations

Abstract

Subretinal injection is a delicate and complex microsurgery, which requires surgeons to inject the therapeutic substance in a pre-operatively defined and intra-operatively updated subretinal target area. Due to the lack of subretinal visual feedback, it is hard to sense the insertion depth during the procedure, thus affecting the results of surgical outcome and hindering the widespread use of this treatment. This paper presents a novel approach to estimate the 3D position of the needle under the retina using the information from microscope-integrated Intraoperative Optical Coherence Tomography (iOCT). We evaluated our approach on both tissue phantom and ex-vivo porcine eyes. Evaluation results show that the average error in distance measurement is 4.7 \mu \text{m} (maximum of 16.5 \mu \text{m}). We furthermore, verified the feasibility of the proposed method to track the insertion depth of needle in robot-assisted subretinal injection.

Original languageEnglish
Title of host publication2018 IEEE International Conference on Robotics and Automation, ICRA 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4033-4040
Number of pages8
ISBN (Electronic)9781538630815
DOIs
StatePublished - 10 Sep 2018
Event2018 IEEE International Conference on Robotics and Automation, ICRA 2018 - Brisbane, Australia
Duration: 21 May 201825 May 2018

Publication series

NameProceedings - IEEE International Conference on Robotics and Automation
ISSN (Print)1050-4729

Conference

Conference2018 IEEE International Conference on Robotics and Automation, ICRA 2018
Country/TerritoryAustralia
CityBrisbane
Period21/05/1825/05/18

Fingerprint

Dive into the research topics of 'Precision Needle Tip Localization Using Optical Coherence Tomography Images for Subretinal Injection'. Together they form a unique fingerprint.

Cite this