Practical imidazole-based phosphine ligands for selective palladium-catalyzed hydroxylation of aryl halides

Thomas Schulz, Christian Torborg, Benjamin Schäffner, Jun Huang, Alexander Zapf, Renat Kadyrov, Armin Börner, Matthias Beller

Research output: Contribution to journalArticlepeer-review

223 Scopus citations

Abstract

(Chemical Equation Presented) The phenol countdown: Novel imidazole-based phosphine ligands are synthesized on scales up to 100 g by a convenient lithiation-phosphorylation method. The phosphines are stable towards air and moisture and are successfully applied as ligands in the palladium-catalyzed selective hydroxylation of aryl halides (see scheme, dba=dibenzylideneacetone).

Original languageEnglish
Pages (from-to)918-921
Number of pages4
JournalAngewandte Chemie International Edition in English
Volume48
Issue number5
DOIs
StatePublished - 19 Jan 2009
Externally publishedYes

Keywords

  • Chemoselectivity
  • Homogeneous catalysis
  • Hydroxylation
  • Palladium
  • Phosphines

Fingerprint

Dive into the research topics of 'Practical imidazole-based phosphine ligands for selective palladium-catalyzed hydroxylation of aryl halides'. Together they form a unique fingerprint.

Cite this