Potential role of somatostatin and octreotide in the management of acute pancreatitis

M. W. Buchler; M. Binder; H. Friess; P. Malfertheiner

doi:10.1159/000201183

Potential role of somatostatin and octreotide in the management of acute pancreatitis

M. W. Buchler, M. Binder, H. Friess, P. Malfertheiner

University of Bern

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

The pathophysiology of acute pancreatitis remains controversial. Activation of digestive enzymes in the pancreas may play an important role in the course of this disease. Therefore, the inhibition of enzyme secretion may be a possible treatment concept. However, it is not clear whether pancreatic secretion continues during the course of acute pancreatitis. In the present paper experimental and clinical studies are reviewed to evaluate the effect of somatostatin and octreotide treatment in acute pancreatitis.

Original language	English
Pages (from-to)	16-19
Number of pages	4
Journal	Digestion
Volume	55
Issue number	SUPPL. 1
DOIs	https://doi.org/10.1159/000201183
State	Published - 1994
Externally published	Yes

Keywords

Acute pancreatitis
Octreotide
Somatostatin

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10.1159/000201183

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abstract = "The pathophysiology of acute pancreatitis remains controversial. Activation of digestive enzymes in the pancreas may play an important role in the course of this disease. Therefore, the inhibition of enzyme secretion may be a possible treatment concept. However, it is not clear whether pancreatic secretion continues during the course of acute pancreatitis. In the present paper experimental and clinical studies are reviewed to evaluate the effect of somatostatin and octreotide treatment in acute pancreatitis.",

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AB - The pathophysiology of acute pancreatitis remains controversial. Activation of digestive enzymes in the pancreas may play an important role in the course of this disease. Therefore, the inhibition of enzyme secretion may be a possible treatment concept. However, it is not clear whether pancreatic secretion continues during the course of acute pancreatitis. In the present paper experimental and clinical studies are reviewed to evaluate the effect of somatostatin and octreotide treatment in acute pancreatitis.

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KW - Octreotide

KW - Somatostatin

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Potential role of somatostatin and octreotide in the management of acute pancreatitis

Abstract

Keywords

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