Abstract
Actin networks cross-linked by natural linkers [Formula presented]-actinin and filamin are generated in giant vesicles by polymerization through ionophore-mediated influx of [Formula presented]. [Formula presented]-actinin induces the formation of randomly linked networks at 25°C which transform at [Formula presented] into spiderweblike gels or ringlike bundles depending on the vesicle size. Muscle filamin forms ringlike structures under all experimental conditions which can supercoil by subsequent [Formula presented] addition. The polymorphism is rationalized in terms of recent models of bivalent ion coupled semiflexible polyelectrolytes and by considering the topology of the linkers.
Original language | English |
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Journal | Physical Review Letters |
Volume | 89 |
Issue number | 16 |
DOIs | |
State | Published - 2002 |