Plasma levels of isosorbide dinitrate and its main metabolites following oral administration of two sustained release formulations in normal man

Keyphrases

• Plasma Parameters 100%
• Oral Administration 100%
• Sustained-release Formulation 100%
• Isosorbide Dinitrate 100%
• Normal Men 100%
• First-order 20%
• Between-person 20%
• Pharmacologically Active 20%
• Pharmacokinetics 20%
• Body Model 20%
• Active Metabolite 20%
• Healthy Male Volunteers 20%
• Zero Order 20%
• One-compartment 20%
• Oral Sustained Release 20%
• Tablet Formulation 20%
• Sustained-release Capsules 20%
• Hard Gelatin Capsules 20%
• Galenic Formulation 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Sustained Release 100%
• Isosorbide Dinitrate 100%
• Elimination 66%
• Tablet 33%
• Galenic Formulation 33%
• Active Metabolite 33%
• Gelatin 33%
• Pharmacokinetics 33%