TY - GEN
T1 - Photon attenuation correction in whole-body PET/MRI using tissue classification
AU - Martinez-Möller, Axel
AU - Souvatzoglou, Michael
AU - Nekolla, Stephan G.
PY - 2010
Y1 - 2010
N2 - A challenge for hybrid PET/MRI imaging is the determination of the photon attenuation map to correct the acquired PET data. Segmentation of adapted MRI sequence data in four tissue classes (background, lungs, fat, and soft tissue) is proposed and evaluated using data from 35 PET/CT whole-body oncological examinations as well as two PET/CT and MRI examinations from the same patients. When reconstructing with the segmented attenuation map, small differences in tumor uptake were observed mainly for osseous lesions, but did not change the clinical interpretation in any case. The method appears to be viable for clinical use.
AB - A challenge for hybrid PET/MRI imaging is the determination of the photon attenuation map to correct the acquired PET data. Segmentation of adapted MRI sequence data in four tissue classes (background, lungs, fat, and soft tissue) is proposed and evaluated using data from 35 PET/CT whole-body oncological examinations as well as two PET/CT and MRI examinations from the same patients. When reconstructing with the segmented attenuation map, small differences in tumor uptake were observed mainly for osseous lesions, but did not change the clinical interpretation in any case. The method appears to be viable for clinical use.
KW - Attenuation correction
KW - Magnetic resonance
KW - Positron emission tomography
UR - http://www.scopus.com/inward/record.url?scp=77955178351&partnerID=8YFLogxK
U2 - 10.1109/ISBI.2010.5490173
DO - 10.1109/ISBI.2010.5490173
M3 - Conference contribution
AN - SCOPUS:77955178351
SN - 9781424441266
T3 - 2010 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Proceedings
SP - 1061
EP - 1062
BT - 2010 7th IEEE International Symposium on Biomedical Imaging
T2 - 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010
Y2 - 14 April 2010 through 17 April 2010
ER -