TY - JOUR
T1 - Photolactonisierung
T2 - Ein neuer synthetischer Zugang zu Makroliden
AU - Quinkert, Gerhard
AU - Billhardt, Uta‐Maria ‐M
AU - Jakob, Harald
AU - Fischer, Gerd
AU - Glenneberg, Jürgen
AU - Nagler, Peter
AU - Autze, Volker
AU - Heim, Nana
AU - Wacker, Manfred
AU - Schwalbe, Thomas
AU - Kurth, Yvonne
AU - Bats, Jan W.
AU - Dürner, Gerd
AU - Zimmermann, Gottfried
AU - Kessler, Horst
PY - 1987/5/6
Y1 - 1987/5/6
N2 - Photolactonization: A Novel Synthetic Entry to Macrolides o‐Quinol acetates, hydroxyalkylated at C(6), are easily accessible from simple phenols by Wessely acetoxylation (preferentially catalyzed by BF3). On UV irradiation (in the presence of an appropriate tertiary amine), they are smoothly converted to macrocyclic lactones. Subtle conditions have been elaborated to lead to high overall yields, and the scope of the conversion of phenols to macrolides has been elucidated.
AB - Photolactonization: A Novel Synthetic Entry to Macrolides o‐Quinol acetates, hydroxyalkylated at C(6), are easily accessible from simple phenols by Wessely acetoxylation (preferentially catalyzed by BF3). On UV irradiation (in the presence of an appropriate tertiary amine), they are smoothly converted to macrocyclic lactones. Subtle conditions have been elaborated to lead to high overall yields, and the scope of the conversion of phenols to macrolides has been elucidated.
UR - https://www.scopus.com/pages/publications/84986381071
U2 - 10.1002/hlca.19870700326
DO - 10.1002/hlca.19870700326
M3 - Artikel
AN - SCOPUS:84986381071
SN - 0018-019X
VL - 70
SP - 771
EP - 861
JO - Helvetica Chimica Acta
JF - Helvetica Chimica Acta
IS - 3
ER -