TY - JOUR
T1 - PET/MR in prostate cancer
T2 - Technical aspects and potential diagnostic value
AU - Souvatzoglou, Michael
AU - Eiber, Matthias
AU - Martinez-Moeller, Axel
AU - Fürst, Sebastian
AU - Holzapfel, Konstantin
AU - Maurer, Tobias
AU - Ziegler, Sibylle
AU - Nekolla, Stephan
AU - Schwaiger, Markus
AU - Beer, Ambros J.
N1 - Funding Information:
Acknowledgments We would like to thank all the patients and their relatives for participating in the studies comparing PET/CT with PET/MR. Furthermore, we thank the whole PET/CT and PET/MR team for their excellent technical assistance as well as the cyclotron team for the reliable tracer supply. The installation of PET/MR in our clinic was funded by the DFG (Deutsche Forschungsgemeinschaft, Grossgeräteinitiative).
PY - 2013
Y1 - 2013
N2 - PET/MR is a new multimodal imaging technique that is expected to improve diagnostic performance of imaging in conditions in which assessment of changes in soft tissue is important such as prostate cancer. Despite substantial changes in PET technology compared to PET/CT, initial studies have demonstrated that integrated PET/MR provides comparable image quality to that of PET/CT, retaining PET quantification efficacy. In this review we briefly describe technological changes compared to PET/CT that made integrated PET/MR possible, propose acquisition protocols for evaluation of prostate cancer with this new multimodal approach, present initial results concerning the application of PET/MR in prostate cancer, and outline the potential for further clinical applications, focusing on potential incremental value compared to present diagnostic performance.
AB - PET/MR is a new multimodal imaging technique that is expected to improve diagnostic performance of imaging in conditions in which assessment of changes in soft tissue is important such as prostate cancer. Despite substantial changes in PET technology compared to PET/CT, initial studies have demonstrated that integrated PET/MR provides comparable image quality to that of PET/CT, retaining PET quantification efficacy. In this review we briefly describe technological changes compared to PET/CT that made integrated PET/MR possible, propose acquisition protocols for evaluation of prostate cancer with this new multimodal approach, present initial results concerning the application of PET/MR in prostate cancer, and outline the potential for further clinical applications, focusing on potential incremental value compared to present diagnostic performance.
KW - Multimodal imaging
KW - PET/CT
KW - PET/MR
KW - Prostate cancer
UR - http://www.scopus.com/inward/record.url?scp=84891586077&partnerID=8YFLogxK
U2 - 10.1007/s00259-013-2445-4
DO - 10.1007/s00259-013-2445-4
M3 - Article
C2 - 23703457
AN - SCOPUS:84891586077
SN - 1619-7070
VL - 40
SP - S79-S88
JO - European Journal of Nuclear Medicine and Molecular Imaging
JF - European Journal of Nuclear Medicine and Molecular Imaging
IS - SUPPL. 1
ER -