Persistent severe amnesia due to seizure recurrence after unilateral temporal lobectomy

Thomas Dietl; Horst Urbach; Christoph Helmstaedter; Mario Staedtgen; Andras Szentkuti; Thomas Grunwald; Bernhard Meyer; Christian Elger; Martin Kurthen

doi:10.1016/j.yebeh.2004.01.004

Persistent severe amnesia due to seizure recurrence after unilateral temporal lobectomy

Thomas Dietl
, Horst Urbach
, Christoph Helmstaedter
, Mario Staedtgen
, Andras Szentkuti
, Thomas Grunwald
, Bernhard Meyer
, Christian Elger
, Martin Kurthen

University of Bonn
Otto-von-Guericke University
Klinik Lengg AG

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Anterograde amnesia is a severely disabling state which has been reported as a consequence of bilateral mesiotemporal lesions in humans. In the present paper, recurrent epileptic seizures after temporal lobectomy are described as a rare cause of severe amnesia in two patients. Diffusion-weighted MRI in one patient showed cytotoxic edema during a nonconvulsive status epilepticus and subsequent progressive hippocampal atrophy within the following month. In the other patient, repeated conventional MRI revealed no structural abnormalities in the contralateral temporal lobe.

Original language	English
Pages (from-to)	394-400
Number of pages	7
Journal	Epilepsy and Behavior
Volume	5
Issue number	3
DOIs	https://doi.org/10.1016/j.yebeh.2004.01.004
State	Published - Jun 2004
Externally published	Yes

Keywords

Amnesia
Amnestic syndrome
Hippocampal sclerosis
Hyperfamiliarity syndrome
Mesiotemporal epilepsy
Temporal lobectomy

Access to Document

10.1016/j.yebeh.2004.01.004

Cite this

@article{62e460f4e07c473281e7deb4a0c7886d,

title = "Persistent severe amnesia due to seizure recurrence after unilateral temporal lobectomy",

abstract = "Anterograde amnesia is a severely disabling state which has been reported as a consequence of bilateral mesiotemporal lesions in humans. In the present paper, recurrent epileptic seizures after temporal lobectomy are described as a rare cause of severe amnesia in two patients. Diffusion-weighted MRI in one patient showed cytotoxic edema during a nonconvulsive status epilepticus and subsequent progressive hippocampal atrophy within the following month. In the other patient, repeated conventional MRI revealed no structural abnormalities in the contralateral temporal lobe.",

keywords = "Amnesia, Amnestic syndrome, Hippocampal sclerosis, Hyperfamiliarity syndrome, Mesiotemporal epilepsy, Temporal lobectomy",

author = "Thomas Dietl and Horst Urbach and Christoph Helmstaedter and Mario Staedtgen and Andras Szentkuti and Thomas Grunwald and Bernhard Meyer and Christian Elger and Martin Kurthen",

note = "Funding Information: T. Dietl's work was supported by the Deutsche Forschungsgemeinschaft (SFB/TR3-A3 and EL 122/4-4). ",

year = "2004",

month = jun,

doi = "10.1016/j.yebeh.2004.01.004",

language = "English",

volume = "5",

pages = "394--400",

journal = "Epilepsy and Behavior",

issn = "1525-5050",

publisher = "Academic Press Inc.",

number = "3",

}

TY - JOUR

T1 - Persistent severe amnesia due to seizure recurrence after unilateral temporal lobectomy

AU - Dietl, Thomas

AU - Urbach, Horst

AU - Helmstaedter, Christoph

AU - Staedtgen, Mario

AU - Szentkuti, Andras

AU - Grunwald, Thomas

AU - Meyer, Bernhard

AU - Elger, Christian

AU - Kurthen, Martin

N1 - Funding Information: T. Dietl's work was supported by the Deutsche Forschungsgemeinschaft (SFB/TR3-A3 and EL 122/4-4).

PY - 2004/6

Y1 - 2004/6

N2 - Anterograde amnesia is a severely disabling state which has been reported as a consequence of bilateral mesiotemporal lesions in humans. In the present paper, recurrent epileptic seizures after temporal lobectomy are described as a rare cause of severe amnesia in two patients. Diffusion-weighted MRI in one patient showed cytotoxic edema during a nonconvulsive status epilepticus and subsequent progressive hippocampal atrophy within the following month. In the other patient, repeated conventional MRI revealed no structural abnormalities in the contralateral temporal lobe.

AB - Anterograde amnesia is a severely disabling state which has been reported as a consequence of bilateral mesiotemporal lesions in humans. In the present paper, recurrent epileptic seizures after temporal lobectomy are described as a rare cause of severe amnesia in two patients. Diffusion-weighted MRI in one patient showed cytotoxic edema during a nonconvulsive status epilepticus and subsequent progressive hippocampal atrophy within the following month. In the other patient, repeated conventional MRI revealed no structural abnormalities in the contralateral temporal lobe.

KW - Amnesia

KW - Amnestic syndrome

KW - Hippocampal sclerosis

KW - Hyperfamiliarity syndrome

KW - Mesiotemporal epilepsy

KW - Temporal lobectomy

UR - https://www.scopus.com/pages/publications/3042663656

U2 - 10.1016/j.yebeh.2004.01.004

DO - 10.1016/j.yebeh.2004.01.004

M3 - Article

C2 - 15145310

AN - SCOPUS:3042663656

SN - 1525-5050

VL - 5

SP - 394

EP - 400

JO - Epilepsy and Behavior

JF - Epilepsy and Behavior

IS - 3

ER -

Persistent severe amnesia due to seizure recurrence after unilateral temporal lobectomy

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this