Peroxide-dependent amino acid oxidation and chemiluminescence catalysed by magnesium-pyridoxal phosphate-glutamate complex

B. U. Meyer; W. Schneider; E. F. Elstner

doi:10.1016/0006-2952(92)90442-L

Peroxide-dependent amino acid oxidation and chemiluminescence catalysed by magnesium-pyridoxal phosphate-glutamate complex

B. U. Meyer, W. Schneider, E. F. Elstner

Life Sciences

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Magnesium-pyridoxal-5′-phosphate-glutamate (MPPG) has been shown to ameliorate atherosclerotic symptoms in rabbits. In vitro, MPPG in the presence of peroxides such as cholesterolhydroperoxide or cumene hydroperoxide and Mn²⁺ ions produces "excited states" measurable as chemiluminescence or ethylene release from 1-aminocyclopropane-1-carboxylic acid (ACC). The reactions are stimulated synergistically by unsaturated fatty acids. Pyridoxal phosphate exhibits similar properties, but can be differentiated from the activities of MPPG or the sum of the components present in MPPG.

Original language	English
Pages (from-to)	505-508
Number of pages	4
Journal	Biochemical Pharmacology
Volume	44
Issue number	3
DOIs	https://doi.org/10.1016/0006-2952(92)90442-L
State	Published - 4 Aug 1992

Access to Document

10.1016/0006-2952(92)90442-L

Cite this

@article{3d1d64dea3114657b65ad52d448135ac,

title = "Peroxide-dependent amino acid oxidation and chemiluminescence catalysed by magnesium-pyridoxal phosphate-glutamate complex",

abstract = "Magnesium-pyridoxal-5′-phosphate-glutamate (MPPG) has been shown to ameliorate atherosclerotic symptoms in rabbits. In vitro, MPPG in the presence of peroxides such as cholesterolhydroperoxide or cumene hydroperoxide and Mn2+ ions produces {"}excited states{"} measurable as chemiluminescence or ethylene release from 1-aminocyclopropane-1-carboxylic acid (ACC). The reactions are stimulated synergistically by unsaturated fatty acids. Pyridoxal phosphate exhibits similar properties, but can be differentiated from the activities of MPPG or the sum of the components present in MPPG.",

author = "Meyer, {B. U.} and W. Schneider and Elstner, {E. F.}",

year = "1992",

month = aug,

day = "4",

doi = "10.1016/0006-2952(92)90442-L",

language = "English",

volume = "44",

pages = "505--508",

journal = "Biochemical Pharmacology",

issn = "0006-2952",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - Peroxide-dependent amino acid oxidation and chemiluminescence catalysed by magnesium-pyridoxal phosphate-glutamate complex

AU - Meyer, B. U.

AU - Schneider, W.

AU - Elstner, E. F.

PY - 1992/8/4

Y1 - 1992/8/4

N2 - Magnesium-pyridoxal-5′-phosphate-glutamate (MPPG) has been shown to ameliorate atherosclerotic symptoms in rabbits. In vitro, MPPG in the presence of peroxides such as cholesterolhydroperoxide or cumene hydroperoxide and Mn2+ ions produces "excited states" measurable as chemiluminescence or ethylene release from 1-aminocyclopropane-1-carboxylic acid (ACC). The reactions are stimulated synergistically by unsaturated fatty acids. Pyridoxal phosphate exhibits similar properties, but can be differentiated from the activities of MPPG or the sum of the components present in MPPG.

AB - Magnesium-pyridoxal-5′-phosphate-glutamate (MPPG) has been shown to ameliorate atherosclerotic symptoms in rabbits. In vitro, MPPG in the presence of peroxides such as cholesterolhydroperoxide or cumene hydroperoxide and Mn2+ ions produces "excited states" measurable as chemiluminescence or ethylene release from 1-aminocyclopropane-1-carboxylic acid (ACC). The reactions are stimulated synergistically by unsaturated fatty acids. Pyridoxal phosphate exhibits similar properties, but can be differentiated from the activities of MPPG or the sum of the components present in MPPG.

UR - http://www.scopus.com/inward/record.url?scp=0026735732&partnerID=8YFLogxK

U2 - 10.1016/0006-2952(92)90442-L

DO - 10.1016/0006-2952(92)90442-L

M3 - Article

C2 - 1510700

AN - SCOPUS:0026735732

SN - 0006-2952

VL - 44

SP - 505

EP - 508

JO - Biochemical Pharmacology

JF - Biochemical Pharmacology

IS - 3

ER -

Peroxide-dependent amino acid oxidation and chemiluminescence catalysed by magnesium-pyridoxal phosphate-glutamate complex

Abstract

Access to Document

Other files and links

Fingerprint

Cite this