Performance Limitations in Heart Transplant Recipients

Wesley J. Tucker, Rhys I. Beaudry, T. Jake Samuel, Michael D. Nelson, Martin Halle, Aaron L. Baggish, Mark J. Haykowsky

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations


We hypothesize that the reduced peak aerobic power (peak VO2) after heart transplantation is due to impaired cardiovascular and skeletal muscle function, and its improvement with short-term (≤1 yr) exercise training is primarily due to favorable skeletal muscle adaptations. Furthermore, the increased peak VO2 with long-term (>2 yr) training is primarily mediated by cardiac (sympathetic) reinnervation.

Original languageEnglish
Pages (from-to)144-151
Number of pages8
JournalExercise and Sport Sciences Reviews
Issue number3
StatePublished - 1 Jul 2018


  • cardiac reinnervation
  • cardiovascular function
  • exercise training
  • peak oxygen uptake
  • skeletal muscle function


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