Performance Limitations in Heart Transplant Recipients

Wesley J. Tucker, Rhys I. Beaudry, T. Jake Samuel, Michael D. Nelson, Martin Halle, Aaron L. Baggish, Mark J. Haykowsky

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations

Abstract

We hypothesize that the reduced peak aerobic power (peak VO2) after heart transplantation is due to impaired cardiovascular and skeletal muscle function, and its improvement with short-term (≤1 yr) exercise training is primarily due to favorable skeletal muscle adaptations. Furthermore, the increased peak VO2 with long-term (>2 yr) training is primarily mediated by cardiac (sympathetic) reinnervation.

Original languageEnglish
Pages (from-to)144-151
Number of pages8
JournalExercise and Sport Sciences Reviews
Volume46
Issue number3
DOIs
StatePublished - 1 Jul 2018

Keywords

  • cardiac reinnervation
  • cardiovascular function
  • exercise training
  • peak oxygen uptake
  • skeletal muscle function

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