Patientenabgeleitete Tumororganoide – ein Therapiemodell für die Präzisionsonkologie

Translated title of the contribution: Patient-derived tumor organoids—a therapeutic model in precision oncology

Linus R. Schömig, Michael Quante

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Organoids are three-dimensional, multicellular and stem-cell-derived in vitro tissue cultures with self-organizing and self-renewing capabilities. In the field of personalized treatment approaches, organoids can serve as a suitable treatment model for molecular and functional analyses, due to their high similarities to the primary tissue that they were derived from. Especially in the field of precision oncology, where a high demand for patient-specific therapy models remains, organoids can serve as an alternative to conventional two-dimensional tissue culture and patient-derived xenografts.

Translated title of the contributionPatient-derived tumor organoids—a therapeutic model in precision oncology
Original languageGerman
Pages (from-to)74-84
Number of pages11
JournalOnkologie
Volume29
Issue number1
DOIs
StatePublished - Jan 2023
Externally publishedYes

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