Pathways to understanding the genomic aetiology of osteoarthritis

Elena Cibrián Uhalte; Jeremy Mark Wilkinson; Lorraine Southam; Eleftheria Zeggini

doi:10.1093/hmg/ddx302

Pathways to understanding the genomic aetiology of osteoarthritis

Elena Cibrián Uhalte, Jeremy Mark Wilkinson, Lorraine Southam, Eleftheria Zeggini

Research output: Contribution to journal › Review article › peer-review

36 Scopus citations

Abstract

Osteoarthritis is a common, complex disease with no curative therapy. In this review, we summarize current knowledge on disease aetiopathogenesis and outline genetics and genomics approaches that are helping catalyse a much-needed improved understanding of the biological underpinning of disease development and progression.

Original language	English
Pages (from-to)	R193-R201
Journal	Human Molecular Genetics
Volume	26
Issue number	R2
DOIs	https://doi.org/10.1093/hmg/ddx302
State	Published - 1 Oct 2017
Externally published	Yes

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AU - Wilkinson, Jeremy Mark

AU - Southam, Lorraine

AU - Zeggini, Eleftheria

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M3 - Review article

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Pathways to understanding the genomic aetiology of osteoarthritis

Abstract

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