Pathologie neuroendokriner Neoplasien

Translated title of the contribution: Pathology of neuroendocrine neoplasms

M. Anlauf, P. Gerlach, M. Schott, A. Raffel, M. Krausch, W. T. Knoefel, M. Pavel, G. Klöppel

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations

Abstract

During the last 5 years the European Neuroendocrine Tumor Society (ENETS) has developed basic recommendations for a standardized pathological diagnosis and classification of neuroendocrine neoplasms (NEN) of the gastroenteropancreatic system. These were included in the novel classification of tumors of the digestive system by the World Health Organization (WHO 2010) and the TNM classification of the union for international cancer control (2009). This review presents the pathology diagnosis regarding (1) basic diagnosis, (2) clinically relevant optional diagnosis, (3) proliferation-based grading, (4) nomenclature and (5) TNM classification. It is emphasized that a standardized diagnosis of NEN, together with clinical and radiological findings, is crucial for prognostic stratification and optimal therapy of patients with NEN. Therefore a close interdisciplinary collaboration is essential.

Translated title of the contributionPathology of neuroendocrine neoplasms
Original languageGerman
Pages (from-to)567-573
Number of pages7
JournalChirurg
Volume82
Issue number7
DOIs
StatePublished - Jul 2011
Externally publishedYes

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