Abstract
Magnetically driven stirred-columns designed for parallel operation in an incubator chamber operated like shaking flasks were characterized with respect to oxygen mass transfer and volume related power input. Power inputs of 770 ± 60 W m-3 were measured at a stirrer speed of 900 rpm, which is in the same order of magnitude as in stirred-tank reactors and shaking flasks. Oxygen mass transfer coefficients of up to 0.34 ± 0.05 s-1 were achieved in stirred-columns (E. coli medium). Due to their similarity to stirred-tank reactors with respect to oxygen mass transfer and power input, parallel-operated stirred-columns may be a useful new tool for microbial process development.
| Original language | English |
|---|---|
| Pages (from-to) | 69-72 |
| Number of pages | 4 |
| Journal | Biochemical Engineering Journal |
| Volume | 11 |
| Issue number | 1 |
| DOIs | |
| State | Published - 2002 |
Keywords
- Aeration
- Bioreactors
- Oxygen transfer
- Power input
- Stirred-column