Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer

Leticia Moreira; Basil Bakir; Priya Chatterji; Zahra Dantes; Maximilian Reichert; Anil K. Rustgi

doi:10.1016/j.jcmgh.2017.12.004

Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer

Leticia Moreira, Basil Bakir, Priya Chatterji, Zahra Dantes, Maximilian Reichert, Anil K. Rustgi

Medicine and Health

Research output: Contribution to journal › Review article › peer-review

77 Scopus citations

Abstract

Pancreatic ductal adenocarcinoma is one of the most aggressive forms of cancer, and the third leading cause of cancer-related mortality in the United States. Although important advances have been made in the last decade, the mortality rate of pancreatic ductal adenocarcinoma has not changed appreciably. This review summarizes a rapidly emerging model of pancreatic cancer research, focusing on 3-dimensional organoids as a powerful tool for several applications, but above all, representing a step toward personalized medicine.

Original language	English
Pages (from-to)	289-298
Number of pages	10
Journal	CMGH
Volume	5
Issue number	3
DOIs	https://doi.org/10.1016/j.jcmgh.2017.12.004
State	Published - Mar 2018

Keywords

3D Organoids
Adenocarcinoma
Pancreas
Personalized Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jcmgh.2017.12.004

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title = "Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer",

abstract = "Pancreatic ductal adenocarcinoma is one of the most aggressive forms of cancer, and the third leading cause of cancer-related mortality in the United States. Although important advances have been made in the last decade, the mortality rate of pancreatic ductal adenocarcinoma has not changed appreciably. This review summarizes a rapidly emerging model of pancreatic cancer research, focusing on 3-dimensional organoids as a powerful tool for several applications, but above all, representing a step toward personalized medicine.",

keywords = "3D Organoids, Adenocarcinoma, Pancreas, Personalized Medicine",

author = "Leticia Moreira and Basil Bakir and Priya Chatterji and Zahra Dantes and Maximilian Reichert and Rustgi, {Anil K.}",

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year = "2018",

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doi = "10.1016/j.jcmgh.2017.12.004",

language = "English",

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pages = "289--298",

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T1 - Pancreas 3D Organoids

T2 - Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer

AU - Moreira, Leticia

AU - Bakir, Basil

AU - Chatterji, Priya

AU - Dantes, Zahra

AU - Reichert, Maximilian

AU - Rustgi, Anil K.

PY - 2018/3

Y1 - 2018/3

N2 - Pancreatic ductal adenocarcinoma is one of the most aggressive forms of cancer, and the third leading cause of cancer-related mortality in the United States. Although important advances have been made in the last decade, the mortality rate of pancreatic ductal adenocarcinoma has not changed appreciably. This review summarizes a rapidly emerging model of pancreatic cancer research, focusing on 3-dimensional organoids as a powerful tool for several applications, but above all, representing a step toward personalized medicine.

AB - Pancreatic ductal adenocarcinoma is one of the most aggressive forms of cancer, and the third leading cause of cancer-related mortality in the United States. Although important advances have been made in the last decade, the mortality rate of pancreatic ductal adenocarcinoma has not changed appreciably. This review summarizes a rapidly emerging model of pancreatic cancer research, focusing on 3-dimensional organoids as a powerful tool for several applications, but above all, representing a step toward personalized medicine.

KW - 3D Organoids

KW - Adenocarcinoma

KW - Pancreas

KW - Personalized Medicine

UR - http://www.scopus.com/inward/record.url?scp=85043596392&partnerID=8YFLogxK

U2 - 10.1016/j.jcmgh.2017.12.004

DO - 10.1016/j.jcmgh.2017.12.004

M3 - Review article

AN - SCOPUS:85043596392

SN - 2352-345X

VL - 5

SP - 289

EP - 298

JO - CMGH

JF - CMGH

IS - 3

ER -

Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer

Abstract

Keywords

UN SDGs

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