TY - JOUR
T1 - Pan-European study of genotypes and phenotypes in the Arabidopsis relative Cardamine hirsuta reveals how adaptation, demography, and development shape diversity patterns
AU - Baumgarten, Lukas
AU - Pieper, Bjorn
AU - Song, Baoxing
AU - Mane, Sébastien
AU - Lempe, Janne
AU - Lamb, Jonathan
AU - Cooke, Elizabeth L.
AU - Srivastava, Rachita
AU - Strütt, Stefan
AU - Žanko, Danijela
AU - Casimiro, Pedro G.P.
AU - Hallab, Asis
AU - Cartolano, Maria
AU - Tattersall, Alexander D.
AU - Huettel, Bruno
AU - Filatov, Dmitry A.
AU - Pavlidis, Pavlos
AU - Neuffer, Barbara
AU - Bazakos, Christos
AU - Schaefer, Hanno
AU - Mott, Richard
AU - Gan, Xiangchao
AU - Alonso-Blanco, Carlos
AU - Laurent, Stefan
AU - Tsiantis, Miltos
N1 - Publisher Copyright:
Copyright: © 2023 Baumgarten et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2023/7
Y1 - 2023/7
N2 - We study natural DNA polymorphisms and associated phenotypes in the Arabidopsis relative Cardamine hirsuta. We observed strong genetic differentiation among several ancestry groups and broader distribution of Iberian relict strains in European C. hirsuta compared to Arabidopsis. We found synchronization between vegetative and reproductive development and a pervasive role for heterochronic pathways in shaping C. hirsuta natural variation. A single, fast-cycling ChFRIGIDA allele evolved adaptively allowing range expansion from glacial refugia, unlike Arabidopsis where multiple FRIGIDA haplotypes were involved. The Azores islands, where Arabidopsis is scarce, are a hotspot for C. hirsuta diversity. We identified a quantitative trait locus (QTL) in the heterochronic SPL9 transcription factor as a determinant of an Azorean morphotype. This QTL shows evidence for positive selection, and its distribution mirrors a climate gradient that broadly shaped the Azorean flora. Overall, we establish a framework to explore how the interplay of adaptation, demography, and development shaped diversity patterns of 2 related plant species.
AB - We study natural DNA polymorphisms and associated phenotypes in the Arabidopsis relative Cardamine hirsuta. We observed strong genetic differentiation among several ancestry groups and broader distribution of Iberian relict strains in European C. hirsuta compared to Arabidopsis. We found synchronization between vegetative and reproductive development and a pervasive role for heterochronic pathways in shaping C. hirsuta natural variation. A single, fast-cycling ChFRIGIDA allele evolved adaptively allowing range expansion from glacial refugia, unlike Arabidopsis where multiple FRIGIDA haplotypes were involved. The Azores islands, where Arabidopsis is scarce, are a hotspot for C. hirsuta diversity. We identified a quantitative trait locus (QTL) in the heterochronic SPL9 transcription factor as a determinant of an Azorean morphotype. This QTL shows evidence for positive selection, and its distribution mirrors a climate gradient that broadly shaped the Azorean flora. Overall, we establish a framework to explore how the interplay of adaptation, demography, and development shaped diversity patterns of 2 related plant species.
UR - http://www.scopus.com/inward/record.url?scp=85165520127&partnerID=8YFLogxK
U2 - 10.1371/journal.pbio.3002191
DO - 10.1371/journal.pbio.3002191
M3 - Article
C2 - 37463141
AN - SCOPUS:85165520127
SN - 1544-9173
VL - 21
JO - PLoS Biology
JF - PLoS Biology
IS - 7 July
M1 - e3002191
ER -
