Palladium-catalyzed coupling reactions: Carbonylative heck reactions to give chalcones

Xiao Feng Wu, Helfried Neumann, Matthias Beller

Research output: Contribution to journalArticlepeer-review

150 Scopus citations

Abstract

Chalcones made easy: Carbonylative Heck reactions of aryl and alkenyl triflate derivatives with carbon monoxide and aromatic olefins proceed in the presence of palladium catalysts (see scheme; dppp=1,3-bis(diphenylphosphino) propane, Tf=triflate; R=aryl, vinyl). With this process, the gap between the Suzuki and Sonogashira carbonylative reactions is finally bridged. "Chemical equation presented"

Original languageEnglish
Pages (from-to)5284-5288
Number of pages5
JournalAngewandte Chemie International Edition in English
Volume49
Issue number31
DOIs
StatePublished - 19 Jul 2010
Externally publishedYes

Keywords

  • Aryl triflates
  • Carbonylation
  • Ketones
  • Palladium
  • Vinylation

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