Palladium-catalyzed carbonylative suzuki coupling of benzyl halides with potassium aryltrifluoroborates in aqueous media

Xiao Feng Wu, Helfried Neumann, Matthias Beller

Research output: Contribution to journalArticlepeer-review

67 Scopus citations

Abstract

A general palladium-catalyzed carbonylative cross-coupling reaction of benzyl chlorides with potassium aryltrifluoroborates in water has been developed. Applying this improved methodology 16 different 1,2-diarylethanones have been synthesized in 40-89% yield.

Original languageEnglish
Pages (from-to)788-792
Number of pages5
JournalAdvanced Synthesis and Catalysis
Volume353
Issue number5
DOIs
StatePublished - 28 Mar 2011
Externally publishedYes

Keywords

  • benzyl chlorides
  • carbonylation
  • palladium
  • potassium aryltrifluoroborates
  • water

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