Palladium catalysts for the formylation of vinyl triflates to form α,β-unsaturated aldehydes

Helfried Neumann, Alexey Sergeev, Matthias Beller

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

(Chemical Equation Presented) What a gas! Synthesis gas is the formylating agent in the efficient one-step title transformation promoted by a palladium catalyst with the bidentate ligand 1,2-bis(di-1-adamantylphosphinomethyl)benzene (see scheme). This method enables the conversion of six-to eight-membered-ring triflates into α,β-unsaturated aldehydes and the introduction of a formyl group into derivatives of elaborate natural compounds. Tf = trifluoromethanesulfonyl.

Original languageEnglish
Pages (from-to)4887-4891
Number of pages5
JournalAngewandte Chemie International Edition in English
Volume47
Issue number26
DOIs
StatePublished - 16 Jun 2008
Externally publishedYes

Keywords

  • Aldehydes
  • Formylation
  • P ligands
  • Palladium
  • Vinyl triflates

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