Abstract
Over the past decade there has been an explosion in our understanding of acute and chronic pain. Much of this progress has come from animal models and from the study of human surrogate models in healthy subjects. These studies have shown that chronic pain probably is not a result of a single pathophysiological mechanism, but rather the end product of an altered peripheral, spinal, and supraspinal processing.
Original language | English |
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Pages (from-to) | 108-109 |
Number of pages | 2 |
Journal | Douleur et Analgesie |
Volume | 19 |
Issue number | 4 |
DOIs | |
State | Published - 2006 |
Keywords
- Brain imaging
- Endogenous opioids
- Neuronal plasticity
- Stimulus-transcription-cascade