Overview of the yeast genome

H. W. Mewes; K. Albermann; M. Bähr; D. Frishman; A. Gleissner; J. Hani; K. Heumann; K. Kleine; A. Maierl; S. G. Oliver; F. Pfeiffer; A. Zollner

doi:10.1038/387s007

Overview of the yeast genome

H. W. Mewes, K. Albermann, M. Bähr, D. Frishman, A. Gleissner, J. Hani, K. Heumann, K. Kleine, A. Maierl, S. G. Oliver, F. Pfeiffer, A. Zollner

Research output: Contribution to journal › Comment/debate

482 Scopus citations

Abstract

The collaboration of more than 600 scientists from over 100 laboratories to sequence the Saccharomyces cerevisiae genome was the largest decentralised experiment in modern molecular biology and resulted in a unique data resource representing the first complete set of genes from a eukaryotic organism. 12 million bases were sequenced in a truly international effort involving European, US, Canadian and Japanese laboratories. While the yeast genome represents only a small fraction of the information in today's public sequence databases, the complete, ordered and non-redundant sequence provides an invaluable resource for the detailed analysis of cellular gene function and genome architecture. In terms of throughput, completeness and information content, yeast has always been the lead eukaryotic organism in genomics; it is still the largest genome to be completely sequenced.

Original language	English
Pages (from-to)	7-8
Number of pages	2
Journal	Nature
Volume	387
Issue number	6632 SUPPL.
DOIs	https://doi.org/10.1038/387s007
State	Published - 29 May 1997
Externally published	Yes

Access to Document

10.1038/387s007

Cite this

@article{8c57f6761b044de4bdf289d1604f3706,

title = "Overview of the yeast genome",

abstract = "The collaboration of more than 600 scientists from over 100 laboratories to sequence the Saccharomyces cerevisiae genome was the largest decentralised experiment in modern molecular biology and resulted in a unique data resource representing the first complete set of genes from a eukaryotic organism. 12 million bases were sequenced in a truly international effort involving European, US, Canadian and Japanese laboratories. While the yeast genome represents only a small fraction of the information in today's public sequence databases, the complete, ordered and non-redundant sequence provides an invaluable resource for the detailed analysis of cellular gene function and genome architecture. In terms of throughput, completeness and information content, yeast has always been the lead eukaryotic organism in genomics; it is still the largest genome to be completely sequenced.",

author = "Mewes, {H. W.} and K. Albermann and M. B{\"a}hr and D. Frishman and A. Gleissner and J. Hani and K. Heumann and K. Kleine and A. Maierl and Oliver, {S. G.} and F. Pfeiffer and A. Zollner",

year = "1997",

month = may,

day = "29",

doi = "10.1038/387s007",

language = "English",

volume = "387",

pages = "7--8",

journal = "Nature",

issn = "0028-0836",

publisher = "Nature Research",

number = "6632 SUPPL.",

}

TY - JOUR

T1 - Overview of the yeast genome

AU - Mewes, H. W.

AU - Albermann, K.

AU - Bähr, M.

AU - Frishman, D.

AU - Gleissner, A.

AU - Hani, J.

AU - Heumann, K.

AU - Kleine, K.

AU - Maierl, A.

AU - Oliver, S. G.

AU - Pfeiffer, F.

AU - Zollner, A.

PY - 1997/5/29

Y1 - 1997/5/29

N2 - The collaboration of more than 600 scientists from over 100 laboratories to sequence the Saccharomyces cerevisiae genome was the largest decentralised experiment in modern molecular biology and resulted in a unique data resource representing the first complete set of genes from a eukaryotic organism. 12 million bases were sequenced in a truly international effort involving European, US, Canadian and Japanese laboratories. While the yeast genome represents only a small fraction of the information in today's public sequence databases, the complete, ordered and non-redundant sequence provides an invaluable resource for the detailed analysis of cellular gene function and genome architecture. In terms of throughput, completeness and information content, yeast has always been the lead eukaryotic organism in genomics; it is still the largest genome to be completely sequenced.

AB - The collaboration of more than 600 scientists from over 100 laboratories to sequence the Saccharomyces cerevisiae genome was the largest decentralised experiment in modern molecular biology and resulted in a unique data resource representing the first complete set of genes from a eukaryotic organism. 12 million bases were sequenced in a truly international effort involving European, US, Canadian and Japanese laboratories. While the yeast genome represents only a small fraction of the information in today's public sequence databases, the complete, ordered and non-redundant sequence provides an invaluable resource for the detailed analysis of cellular gene function and genome architecture. In terms of throughput, completeness and information content, yeast has always been the lead eukaryotic organism in genomics; it is still the largest genome to be completely sequenced.

UR - http://www.scopus.com/inward/record.url?scp=8544240102&partnerID=8YFLogxK

U2 - 10.1038/387s007

DO - 10.1038/387s007

M3 - Comment/debate

C2 - 9169865

AN - SCOPUS:8544240102

SN - 0028-0836

VL - 387

SP - 7

EP - 8

JO - Nature

JF - Nature

IS - 6632 SUPPL.

ER -

Overview of the yeast genome

Abstract

Access to Document

Other files and links

Fingerprint

Cite this