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Over 1000 tools reveal trends in the single-cell RNA-seq analysis landscape

  • Helmholtz Zentrum München German Research Center for Environmental Health
  • Technical University of Munich

Research output: Contribution to journalReview articlepeer-review

120 Scopus citations

Abstract

Recent years have seen a revolution in single-cell RNA-sequencing (scRNA-seq) technologies, datasets, and analysis methods. Since 2016, the scRNA-tools database has cataloged software tools for analyzing scRNA-seq data. With the number of tools in the database passing 1000, we provide an update on the state of the project and the field. This data shows the evolution of the field and a change of focus from ordering cells on continuous trajectories to integrating multiple samples and making use of reference datasets. We also find that open science practices reward developers with increased recognition and help accelerate the field.

Original languageEnglish
Article number301
JournalGenome Biology
Volume22
Issue number1
DOIs
StatePublished - Dec 2021

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