Osteogenesis imperfecta and hyperplastic callus formation: Light- and electron-microscopic findings

H. Stoss, B. Pontz, U. Vetter, A. Karbowski, R. Brenner, J. Spranger

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

In rare cases of osteogenesis imperfecta, an 'overshoot' growth of new bone may occur, which, clinically gives the impression of a tumour. This condition is known as hyperplastic callus formation. Morphology showed an excessive mixed desmal-chondral osteoneogenesis. Atypical collagen fibrils in non-callus tissue represent an indicator for this callus formation in individual patients.

Original languageEnglish
Pages (from-to)260
Number of pages1
JournalAmerican Journal of Medical Genetics
Volume45
Issue number2
DOIs
StatePublished - 1993
Externally publishedYes

Keywords

  • atypical collagen fibrils
  • desmalchondral osteoneogenesis
  • hyperplastic callus
  • osteogenesis imperfecta

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