Osseous integration of bovine hydroxyapatite ceramic in metaphyseal bone defects of the distal radius

Klaus Dieter Werber, Robert B. Brauer, Wolfgang Weiß, Karen Becker

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Hydroxyapatite ceramic made of bovine spongiosa was used as structural support material in a prospective study to correct bone defects experienced after reduction in distal radius fractures. The study took place over a 3-year period (1992-1999) and comprised 14 patients. Osseous integration was analyzed via biopsies and magnetic resonance imaging. Long-term follow-up monitoring involving magnetic resonance imaging in 13 of the 14 patients showed fibrovascular growth within incorporated hydroxyapatite material. Osseous integration was demonstrated in magnetic resonance images by gadolinium uptake and by the presence of osteoid layers and endothelialized vessels. Hydroxyapatite ceramic offers a biologically acceptable alternative to autologous bone when augmenting distal radius fracture fixation. Copyright (C) 2000 by the American Society for Surgery of the Hand.

Original languageEnglish
Pages (from-to)833-841
Number of pages9
JournalJournal of Hand Surgery
Volume25
Issue number5
DOIs
StatePublished - 2000
Externally publishedYes

Keywords

  • Bone defects
  • Distal radius fracture
  • Hydroxyapatite ceramic
  • Osseous integration

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