Orthogonal polarization spectral (OPS) imaging: A new technique for the visualization and study of the microcirculation

A. G. Harris; I. Sinitsina; S. Pahernik; S. Langer; E. von Dobschuetz; P. Biberthaler; E. Uhl; O. Genzel; K. Messmer

doi:10.1117/12.431552

Orthogonal polarization spectral (OPS) imaging: A new technique for the visualization and study of the microcirculation

A. G. Harris
, I. Sinitsina
, S. Pahernik
, S. Langer
, E. von Dobschuetz
, P. Biberthaler
, E. Uhl
, O. Genzel
, K. Messmer

Research output: Contribution to journal › Article › peer-review

Abstract

OPS-imaging was incorporated into a small, hand held device which is easily transportable (CYTOSCAN). Following this, the CYTOSCAN device was evaluated and validated for microvascular measurements against standard intravital fluorescence microscopy (IFM) in a variety of animal models. The results suggest that OPS-imaging can be used to make quantitative measurements of the microcirculation in animal models as well as in human subjects.

Original language	English
Pages (from-to)	398-408
Number of pages	11
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	4241
DOIs	https://doi.org/10.1117/12.431552
State	Published - 2001
Externally published	Yes

Keywords

Diameter
Functional capillary density
Human
Instrumentation
Intravital microscopy
Microcirculation
OPS imaging
Red blood cells
Validation
Velocity

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10.1117/12.431552

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Harris, A. G., Sinitsina, I., Pahernik, S., Langer, S., von Dobschuetz, E., Biberthaler, P., Uhl, E., Genzel, O., & Messmer, K. (2001). Orthogonal polarization spectral (OPS) imaging: A new technique for the visualization and study of the microcirculation. Proceedings of SPIE - The International Society for Optical Engineering, 4241, 398-408. https://doi.org/10.1117/12.431552

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title = "Orthogonal polarization spectral (OPS) imaging: A new technique for the visualization and study of the microcirculation",

abstract = "OPS-imaging was incorporated into a small, hand held device which is easily transportable (CYTOSCAN). Following this, the CYTOSCAN device was evaluated and validated for microvascular measurements against standard intravital fluorescence microscopy (IFM) in a variety of animal models. The results suggest that OPS-imaging can be used to make quantitative measurements of the microcirculation in animal models as well as in human subjects.",

keywords = "Diameter, Functional capillary density, Human, Instrumentation, Intravital microscopy, Microcirculation, OPS imaging, Red blood cells, Validation, Velocity",

author = "Harris, \{A. G.\} and I. Sinitsina and S. Pahernik and S. Langer and \{von Dobschuetz\}, E. and P. Biberthaler and E. Uhl and O. Genzel and K. Messmer",

year = "2001",

doi = "10.1117/12.431552",

language = "English",

volume = "4241",

pages = "398--408",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

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Harris, AG, Sinitsina, I, Pahernik, S, Langer, S, von Dobschuetz, E, Biberthaler, P, Uhl, E, Genzel, O & Messmer, K 2001, 'Orthogonal polarization spectral (OPS) imaging: A new technique for the visualization and study of the microcirculation', Proceedings of SPIE - The International Society for Optical Engineering, vol. 4241, pp. 398-408. https://doi.org/10.1117/12.431552

TY - JOUR

T1 - Orthogonal polarization spectral (OPS) imaging

T2 - A new technique for the visualization and study of the microcirculation

AU - Harris, A. G.

AU - Sinitsina, I.

AU - Pahernik, S.

AU - Langer, S.

AU - von Dobschuetz, E.

AU - Biberthaler, P.

AU - Uhl, E.

AU - Genzel, O.

AU - Messmer, K.

PY - 2001

Y1 - 2001

N2 - OPS-imaging was incorporated into a small, hand held device which is easily transportable (CYTOSCAN). Following this, the CYTOSCAN device was evaluated and validated for microvascular measurements against standard intravital fluorescence microscopy (IFM) in a variety of animal models. The results suggest that OPS-imaging can be used to make quantitative measurements of the microcirculation in animal models as well as in human subjects.

AB - OPS-imaging was incorporated into a small, hand held device which is easily transportable (CYTOSCAN). Following this, the CYTOSCAN device was evaluated and validated for microvascular measurements against standard intravital fluorescence microscopy (IFM) in a variety of animal models. The results suggest that OPS-imaging can be used to make quantitative measurements of the microcirculation in animal models as well as in human subjects.

KW - Diameter

KW - Functional capillary density

KW - Human

KW - Instrumentation

KW - Intravital microscopy

KW - Microcirculation

KW - OPS imaging

KW - Red blood cells

KW - Validation

KW - Velocity

UR - https://www.scopus.com/pages/publications/0034876151

U2 - 10.1117/12.431552

DO - 10.1117/12.431552

M3 - Article

AN - SCOPUS:0034876151

SN - 0277-786X

VL - 4241

SP - 398

EP - 408

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

ER -

Orthogonal polarization spectral (OPS) imaging: A new technique for the visualization and study of the microcirculation

Abstract

Keywords

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