Orthogonal polarization spectral (OPS) imaging: A new technique for the visualization and study of the microcirculation

A. G. Harris; I. Sinitsina; S. Pahernik; S. Langer; E. von Dobschuetz; P. Biberthaler; E. Uhl; O. Genzel; K. Messmer

doi:10.1117/12.431552

Orthogonal polarization spectral (OPS) imaging: A new technique for the visualization and study of the microcirculation

A. G. Harris, I. Sinitsina, S. Pahernik, S. Langer, E. von Dobschuetz, P. Biberthaler, E. Uhl, O. Genzel, K. Messmer

Research output: Contribution to journal › Article › peer-review

Abstract

OPS-imaging was incorporated into a small, hand held device which is easily transportable (CYTOSCAN). Following this, the CYTOSCAN device was evaluated and validated for microvascular measurements against standard intravital fluorescence microscopy (IFM) in a variety of animal models. The results suggest that OPS-imaging can be used to make quantitative measurements of the microcirculation in animal models as well as in human subjects.

Original language	English
Pages (from-to)	398-408
Number of pages	11
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	4241
DOIs	https://doi.org/10.1117/12.431552
State	Published - 2001
Externally published	Yes

Keywords

Diameter
Functional capillary density
Human
Instrumentation
Intravital microscopy
Microcirculation
OPS imaging
Red blood cells
Validation
Velocity

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Harris, A. G., Sinitsina, I., Pahernik, S., Langer, S., von Dobschuetz, E., Biberthaler, P., Uhl, E., Genzel, O., & Messmer, K. (2001). Orthogonal polarization spectral (OPS) imaging: A new technique for the visualization and study of the microcirculation. Proceedings of SPIE - The International Society for Optical Engineering, 4241, 398-408. https://doi.org/10.1117/12.431552

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title = "Orthogonal polarization spectral (OPS) imaging: A new technique for the visualization and study of the microcirculation",

abstract = "OPS-imaging was incorporated into a small, hand held device which is easily transportable (CYTOSCAN). Following this, the CYTOSCAN device was evaluated and validated for microvascular measurements against standard intravital fluorescence microscopy (IFM) in a variety of animal models. The results suggest that OPS-imaging can be used to make quantitative measurements of the microcirculation in animal models as well as in human subjects.",

keywords = "Diameter, Functional capillary density, Human, Instrumentation, Intravital microscopy, Microcirculation, OPS imaging, Red blood cells, Validation, Velocity",

author = "Harris, {A. G.} and I. Sinitsina and S. Pahernik and S. Langer and {von Dobschuetz}, E. and P. Biberthaler and E. Uhl and O. Genzel and K. Messmer",

year = "2001",

doi = "10.1117/12.431552",

language = "English",

volume = "4241",

pages = "398--408",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

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Harris, AG, Sinitsina, I, Pahernik, S, Langer, S, von Dobschuetz, E, Biberthaler, P, Uhl, E, Genzel, O & Messmer, K 2001, 'Orthogonal polarization spectral (OPS) imaging: A new technique for the visualization and study of the microcirculation', Proceedings of SPIE - The International Society for Optical Engineering, vol. 4241, pp. 398-408. https://doi.org/10.1117/12.431552

TY - JOUR

T1 - Orthogonal polarization spectral (OPS) imaging

T2 - A new technique for the visualization and study of the microcirculation

AU - Harris, A. G.

AU - Sinitsina, I.

AU - Pahernik, S.

AU - Langer, S.

AU - von Dobschuetz, E.

AU - Biberthaler, P.

AU - Uhl, E.

AU - Genzel, O.

AU - Messmer, K.

PY - 2001

Y1 - 2001

N2 - OPS-imaging was incorporated into a small, hand held device which is easily transportable (CYTOSCAN). Following this, the CYTOSCAN device was evaluated and validated for microvascular measurements against standard intravital fluorescence microscopy (IFM) in a variety of animal models. The results suggest that OPS-imaging can be used to make quantitative measurements of the microcirculation in animal models as well as in human subjects.

AB - OPS-imaging was incorporated into a small, hand held device which is easily transportable (CYTOSCAN). Following this, the CYTOSCAN device was evaluated and validated for microvascular measurements against standard intravital fluorescence microscopy (IFM) in a variety of animal models. The results suggest that OPS-imaging can be used to make quantitative measurements of the microcirculation in animal models as well as in human subjects.

KW - Diameter

KW - Functional capillary density

KW - Human

KW - Instrumentation

KW - Intravital microscopy

KW - Microcirculation

KW - OPS imaging

KW - Red blood cells

KW - Validation

KW - Velocity

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DO - 10.1117/12.431552

M3 - Article

AN - SCOPUS:0034876151

SN - 0277-786X

VL - 4241

SP - 398

EP - 408

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

ER -

Orthogonal polarization spectral (OPS) imaging: A new technique for the visualization and study of the microcirculation

Abstract

Keywords

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