Oral soft tissue infections: causes, therapeutic approaches and microbiological spectrum with focus on antibiotic treatment

Carolin Götz, Edeltraud Reinhart, Klaus Dietrich Wolff, Andreas Kolk

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4 Scopus citations


Introduction Intraoral soft tissue infections (OSTI) are a common problem in dentistry and oral surgery. These abscesses are mostly exacerbated dental infections (OIDC), and some emerge as postoperative infections (POI) after tooth extraction (OITR) or apicoectomy (OIRR). The main aim of this study was to compare OIDC with POI, especially looking at the bacteria involved. An additional question was, therefore, if different antibiotic treatments should be used with OSTI of differing aetiologies. The impact of third molars on OSTI was evaluated and also the rates of POI after removal of third molars were specified. Material and methods Patient data was collected from the patients' medical records and the results were statistically evaluated with SPSS (SPSS version 21.0; SPSS, IBM; Chicago, IL, USA). The inclusion criterion was the outpatient treatment of a patient with an exacerbated oral infection; the exclusion criteria were an early stage of infiltration without abscess formation; and a need for inpatient treatment. Results Periapical exacerbated infections, especially in the molar region were the commonest cause of OIDC. In the OITR group, mandibular tooth removal was the commonest factor (p = 0.016). Remarkably, retained lower wisdom teeth led to significant number of cases in the OITR group (p = 0.022). Conclusions In our study we could not define differences between the causal bacteria found in patients with OIDC and POI. Due to resistance rates we conclude that amoxicillin combined with clavulanic acid seems to be the antibiotic standard for exacerbated intraoral infections independent of their aetiology.

Original languageEnglish
Pages (from-to)1849-1854
Number of pages6
JournalJournal of Cranio-Maxillofacial Surgery
Issue number9
StatePublished - Nov 2015
Externally publishedYes


  • Antibiotic resistance
  • Antibiotics in oral surgery
  • Oral soft tissue infections
  • Postoperative complications
  • Third molar surgery


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