Optoacoustic microscopy based on pi-FBG ultrasound sensors

Georg Wissmeyer; Rami Shnaiderman; Dominik Soliman; Vasilis Ntziachristos

doi:10.1117/12.2253066

Optoacoustic microscopy based on pi-FBG ultrasound sensors

Georg Wissmeyer, Rami Shnaiderman, Dominik Soliman, Vasilis Ntziachristos

Chair of Biological Imaging

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

6 Scopus citations

Abstract

We present an optoacoustic (photoacoustic) microscopy (OAM) imaging system that uses a pi-shifted Fiber Bragg Grating (pi-FBG) as ultrasound (US) sensor. The sensor has an ultra-small footprint and hence allows for the detection of optoacoustic signals in close proximity to their origin. The interrogation of the pi-FBG is performed by a broadband pulsed laser, enabling a high sensitivity of the sensor as well as the elimination of ambient noise. We characterize the pi-FBG in terms of axial and lateral resolution as well as its bandwidth and find that its performance is comparable to US sensors that are based on the piezoelectric effect. We demonstrate the system's capabilities by images taken from ex vivo zebrafish and mouse ear samples. The results presented herein highlight that pi-FBGs are a promising tool for the comprehensive label-free optoacoustic imaging of biomedical samples.

Original language	English
Title of host publication	Photons Plus Ultrasound
Subtitle of host publication	Imaging and Sensing 2017
Editors	Alexander A. Oraevsky, Lihong V. Wang
Publisher	SPIE
ISBN (Electronic)	9781510605695
DOIs	https://doi.org/10.1117/12.2253066
State	Published - 2017
Event	Photons Plus Ultrasound: Imaging and Sensing 2017 - San Francisco, United States Duration: 29 Jan 2017 → 1 Feb 2017

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10064
ISSN (Print)	1605-7422

Conference

Conference	Photons Plus Ultrasound: Imaging and Sensing 2017
Country/Territory	United States
City	San Francisco
Period	29/01/17 → 1/02/17

Keywords

Fiber Bragg-Grating
Interferometric detection of ultrasound
Optoacoustic microscopy
Photoacoustic microscopy

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10.1117/12.2253066

Cite this

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title = "Optoacoustic microscopy based on pi-FBG ultrasound sensors",

abstract = "We present an optoacoustic (photoacoustic) microscopy (OAM) imaging system that uses a pi-shifted Fiber Bragg Grating (pi-FBG) as ultrasound (US) sensor. The sensor has an ultra-small footprint and hence allows for the detection of optoacoustic signals in close proximity to their origin. The interrogation of the pi-FBG is performed by a broadband pulsed laser, enabling a high sensitivity of the sensor as well as the elimination of ambient noise. We characterize the pi-FBG in terms of axial and lateral resolution as well as its bandwidth and find that its performance is comparable to US sensors that are based on the piezoelectric effect. We demonstrate the system's capabilities by images taken from ex vivo zebrafish and mouse ear samples. The results presented herein highlight that pi-FBGs are a promising tool for the comprehensive label-free optoacoustic imaging of biomedical samples.",

keywords = "Fiber Bragg-Grating, Interferometric detection of ultrasound, Optoacoustic microscopy, Photoacoustic microscopy",

author = "Georg Wissmeyer and Rami Shnaiderman and Dominik Soliman and Vasilis Ntziachristos",

note = "Publisher Copyright: {\textcopyright} 2017 SPIE.; Photons Plus Ultrasound: Imaging and Sensing 2017 ; Conference date: 29-01-2017 Through 01-02-2017",

year = "2017",

doi = "10.1117/12.2253066",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

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editor = "Oraevsky, {Alexander A.} and Wang, {Lihong V.}",

booktitle = "Photons Plus Ultrasound",

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Wissmeyer, G, Shnaiderman, R, Soliman, D & Ntziachristos, V 2017, Optoacoustic microscopy based on pi-FBG ultrasound sensors. in AA Oraevsky & LV Wang (eds), Photons Plus Ultrasound: Imaging and Sensing 2017., 1006423, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10064, SPIE, Photons Plus Ultrasound: Imaging and Sensing 2017, San Francisco, United States, 29/01/17. https://doi.org/10.1117/12.2253066

Optoacoustic microscopy based on pi-FBG ultrasound sensors. / Wissmeyer, Georg; Shnaiderman, Rami; Soliman, Dominik et al.
Photons Plus Ultrasound: Imaging and Sensing 2017. ed. / Alexander A. Oraevsky; Lihong V. Wang. SPIE, 2017. 1006423 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10064).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Optoacoustic microscopy based on pi-FBG ultrasound sensors

AU - Wissmeyer, Georg

AU - Shnaiderman, Rami

AU - Soliman, Dominik

AU - Ntziachristos, Vasilis

PY - 2017

Y1 - 2017

N2 - We present an optoacoustic (photoacoustic) microscopy (OAM) imaging system that uses a pi-shifted Fiber Bragg Grating (pi-FBG) as ultrasound (US) sensor. The sensor has an ultra-small footprint and hence allows for the detection of optoacoustic signals in close proximity to their origin. The interrogation of the pi-FBG is performed by a broadband pulsed laser, enabling a high sensitivity of the sensor as well as the elimination of ambient noise. We characterize the pi-FBG in terms of axial and lateral resolution as well as its bandwidth and find that its performance is comparable to US sensors that are based on the piezoelectric effect. We demonstrate the system's capabilities by images taken from ex vivo zebrafish and mouse ear samples. The results presented herein highlight that pi-FBGs are a promising tool for the comprehensive label-free optoacoustic imaging of biomedical samples.

AB - We present an optoacoustic (photoacoustic) microscopy (OAM) imaging system that uses a pi-shifted Fiber Bragg Grating (pi-FBG) as ultrasound (US) sensor. The sensor has an ultra-small footprint and hence allows for the detection of optoacoustic signals in close proximity to their origin. The interrogation of the pi-FBG is performed by a broadband pulsed laser, enabling a high sensitivity of the sensor as well as the elimination of ambient noise. We characterize the pi-FBG in terms of axial and lateral resolution as well as its bandwidth and find that its performance is comparable to US sensors that are based on the piezoelectric effect. We demonstrate the system's capabilities by images taken from ex vivo zebrafish and mouse ear samples. The results presented herein highlight that pi-FBGs are a promising tool for the comprehensive label-free optoacoustic imaging of biomedical samples.

KW - Fiber Bragg-Grating

KW - Interferometric detection of ultrasound

KW - Optoacoustic microscopy

KW - Photoacoustic microscopy

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DO - 10.1117/12.2253066

M3 - Conference contribution

AN - SCOPUS:85019201748

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Photons Plus Ultrasound

A2 - Oraevsky, Alexander A.

A2 - Wang, Lihong V.

PB - SPIE

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Y2 - 29 January 2017 through 1 February 2017

ER -

Optoacoustic microscopy based on pi-FBG ultrasound sensors

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Keywords

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