Optimization of tube voltage in X-ray dark-field chest radiography

Andreas P. Sauter, Jana Andrejewski, Fabio De Marco, Konstantin Willer, Lukas B. Gromann, Wolfgang Noichl, Fabian Kriner, Florian Fischer, Christian Braun, Thomas Koehler, Felix Meurer, Alexander A. Fingerle, Daniela Pfeiffer, Ernst Rummeny, Julia Herzen, Franz Pfeiffer

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


Grating-based X-ray dark-field imaging is a novel imaging modality which has been refined during the last decade. It exploits the wave-like behaviour of X-radiation and can nowadays be implemented with existing X-ray tubes used in clinical applications. The method is based on the detection of small-angle X-ray scattering, which occurs e.g. at air-tissue-interfaces in the lung or bone-fat interfaces in spongy bone. In contrast to attenuation-based chest X-ray imaging, the optimal tube voltage for dark-field imaging of the thorax has not yet been examined. In this work, dark-field scans with tube voltages ranging from 60 to 120 kVp were performed on a deceased human body. We analyzed the resulting images with respect to subjective and objective image quality, and found that the optimum tube voltage for dark-field thorax imaging at the used setup is at rather low energies of around 60 to 70 kVp. Furthermore, we found that at these tube voltages, the transmission radiographs still exhibit sufficient image quality to correlate dark-field information. Therefore, this study may serve as an important guideline for the development of clinical dark-field chest X-ray imaging devices for future routine use.

Original languageEnglish
Article number8699
JournalScientific Reports
Issue number1
StatePublished - 1 Dec 2019


Dive into the research topics of 'Optimization of tube voltage in X-ray dark-field chest radiography'. Together they form a unique fingerprint.

Cite this