Operation Kinetics of a DNA-Based Molecular Switch

Friedrich C. Simmel, Bernard Yurke, Rishi J. Sanyal

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


The influence of temperature variation, salt concentration, and pH on the operation kinetics of a simple DNA-based molecular switch is investigated. The device shows robust behavior over a wide range of temperatures, pH, and salt concentrations. In particular, the device operates well under physiological conditions. The experimental data can be qualitatively understood in terms of the influence temperature, salt concentration, and pH have on DNA strand interactions.

Original languageEnglish
Pages (from-to)383-390
Number of pages8
JournalJournal of Nanoscience and Nanotechnology
Issue number3-4
StatePublished - Jun 2002
Externally publishedYes


  • DNA
  • Molecular Machines
  • Self-Assembly


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