Abstract
The review begins by providing a brief typology of biological databases on the Internet, illustrated by examples of the most influential resources of each kind. We then take an insider look at one typical on-line genomic resource - the yeast genome database hosted at the Munich Information Center for Protein Sequences (MIPS) - and explain how and why it has evolved from a basic sequence repository to a multidomain knowledge base. The role of community efforts in curating and annotating genome data is discussed. The crucial role of data integration and interoperability in developing next-generation genomic facilities is underscored.
| Original language | English |
|---|---|
| Pages (from-to) | 265-271 |
| Number of pages | 7 |
| Journal | Pharmacogenomics |
| Volume | 3 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2002 |
Keywords
- Bioinformatics
- Database
- Genome analysis
- Integration
- Internet
- Proteomics
- Structural genomics