TY - JOUR
T1 - Oleanane-type triterpenes of Embelia schimperi leaves
AU - Manguro, Lawrence Onyango Arot
AU - Onyango Okwiri, Steve
AU - Lemmen, Peter
PY - 2006/12
Y1 - 2006/12
N2 - An investigation of an ethyl acetate extract of Embelia schimperi leaves has led to the isolation of 10 oleanane-type triterpenes characterized as 3β,16α-di-O-acetyl-13β, 28-epoxyoleanane (1), 3β-acetyl-16-oxo-13β, 28-epoxyoleanane (2), 3β-acetyl-16α-hydroxy-13β, 28-epoxyoleanane (3), 3β-acetyl-16α-hydroxyoleanane-13β, 28-olide (4), 3β-acetyl-28-hydroxy-16-oxo-12-oleanene (5), 3β, 28-di-O-acetyl-16α-hydroxy-12-oleanene (6), 3β-acetyl-11α, 28-dihydroxy-16-oxo-12-oleanene (7), 3β, 11α, 16α, 28-tetrahydroxy-12-oleanene (8), 3β-acetyl-16α, 28α-dihydroxy-13β, 28-oxydooleanane (9) and 3β, 28α-dihydroxy-16-oxo-13β, 28-oxydooleanane (10). The known compounds isolated from the same extract included 3β, 16α-dihydroxy-13β, 28-epoxyoleanane (protoprimulagenin A) (11), 3β-hydroxy-16-oxo-13β, 28-epoxyoxyoleanane (aegicerin) (12), 3, 16-dioxo-13β, 28-epoxyoleanane (embilionone) (13), 3β, 28-dihydroxy-16-oxo-12-oleanene (schimperinone) (14), taraxerone (15), taraxerol (16) and stigmasterol (17). Structure elucidations were carried out spectroscopically.
AB - An investigation of an ethyl acetate extract of Embelia schimperi leaves has led to the isolation of 10 oleanane-type triterpenes characterized as 3β,16α-di-O-acetyl-13β, 28-epoxyoleanane (1), 3β-acetyl-16-oxo-13β, 28-epoxyoleanane (2), 3β-acetyl-16α-hydroxy-13β, 28-epoxyoleanane (3), 3β-acetyl-16α-hydroxyoleanane-13β, 28-olide (4), 3β-acetyl-28-hydroxy-16-oxo-12-oleanene (5), 3β, 28-di-O-acetyl-16α-hydroxy-12-oleanene (6), 3β-acetyl-11α, 28-dihydroxy-16-oxo-12-oleanene (7), 3β, 11α, 16α, 28-tetrahydroxy-12-oleanene (8), 3β-acetyl-16α, 28α-dihydroxy-13β, 28-oxydooleanane (9) and 3β, 28α-dihydroxy-16-oxo-13β, 28-oxydooleanane (10). The known compounds isolated from the same extract included 3β, 16α-dihydroxy-13β, 28-epoxyoleanane (protoprimulagenin A) (11), 3β-hydroxy-16-oxo-13β, 28-epoxyoxyoleanane (aegicerin) (12), 3, 16-dioxo-13β, 28-epoxyoleanane (embilionone) (13), 3β, 28-dihydroxy-16-oxo-12-oleanene (schimperinone) (14), taraxerone (15), taraxerol (16) and stigmasterol (17). Structure elucidations were carried out spectroscopically.
KW - Embelia schimperi
KW - Leaves
KW - Myrsinaceae
KW - Oleanane tritrpenes
UR - http://www.scopus.com/inward/record.url?scp=33751184380&partnerID=8YFLogxK
U2 - 10.1016/j.phytochem.2006.07.025
DO - 10.1016/j.phytochem.2006.07.025
M3 - Article
C2 - 16973190
AN - SCOPUS:33751184380
SN - 0031-9422
VL - 67
SP - 2641
EP - 2650
JO - Phytochemistry
JF - Phytochemistry
IS - 24
ER -