Odd-numbered medium-chain triglycerides (Trinonanoin) in total parenteral nutrition: Parameters of carbohydrate and protein metabolism

J. Linseisen, G. Wolfram

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

To investigate the metabolic effects of intravenously administered odd-numbered medium-chain triglycerides in healthy non-stressed animals, trinonanoin/long-chain triglyceride (LCT) (7/3) fat emulsions were given in a high dose (46.5% energy) to rabbits (n = 8) for 11 days within a total parenteral nutrition regimen. In comparison with medium-chain triglyceride (MCT)/LCT fat emulsions, higher plasma glucose (day 4), plasma lactate and pyruvate (day 11) and liver glycogen concentrations were found for the test group, indicating a glucogenic effect of the trinonanoin/LCT emulsion. With the present study design, nitrogen balance of the rabbits was not significantly influenced by the kind of fat emulsion administered.

Original languageEnglish
Pages (from-to)320-327
Number of pages8
JournalAnnals of Nutrition and Metabolism
Volume37
Issue number6
DOIs
StatePublished - 1993
Externally publishedYes

Keywords

  • Fat metabolism
  • Medium-chain triglycerides
  • Odd-numbered trinonanoin
  • Parenteral nutrition
  • Rabbits

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