Abstract
The effect of novobiocin on macromolecule synthesis was investigated in Escherichia coli cells permeabilized by treatment with toluene or 2 m-sucrose. It was found that (1) semiconservative DNA replication is strongly and immediately inhibited and (2) ATP-independent DNA repair as well as RNA and protein synthesis are not affected.
| Original language | English |
|---|---|
| Pages (from-to) | 201-205 |
| Number of pages | 5 |
| Journal | Journal of Molecular Biology |
| Volume | 96 |
| Issue number | 1 |
| DOIs | |
| State | Published - 25 Jul 1975 |
| Externally published | Yes |