Normalized Born ratio for fluorescence optical projection tomography

Claudio Vinegoni; Daniel Razansky; Jose Luiz Figueiredo; Matthias Nahrendorf; Vasilis Ntziachristos; Ralph Weissleder

doi:10.1364/OL.34.000319

Normalized Born ratio for fluorescence optical projection tomography

Claudio Vinegoni, Daniel Razansky, Jose Luiz Figueiredo, Matthias Nahrendorf, Vasilis Ntziachristos, Ralph Weissleder

Massachusetts General Hospital

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

We present a normalized Born approach for fluorescence optical projection tomography that takes into account tissue absorption properties. This approach can be particularly useful to study fluorochrome distribution within tissue. We use the algorithm to three-dimensionally reconstruct and characterize a fluorescein isothiocyanate containing absorptive phantom and an infarcted mouse heart previously injected with a fluorescent molecular probe.

Original language	English
Pages (from-to)	319-321
Number of pages	3
Journal	Optics Letters
Volume	34
Issue number	3
DOIs	https://doi.org/10.1364/OL.34.000319
State	Published - 1 Feb 2009

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10.1364/OL.34.000319

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title = "Normalized Born ratio for fluorescence optical projection tomography",

abstract = "We present a normalized Born approach for fluorescence optical projection tomography that takes into account tissue absorption properties. This approach can be particularly useful to study fluorochrome distribution within tissue. We use the algorithm to three-dimensionally reconstruct and characterize a fluorescein isothiocyanate containing absorptive phantom and an infarcted mouse heart previously injected with a fluorescent molecular probe.",

author = "Claudio Vinegoni and Daniel Razansky and Figueiredo, {Jose Luiz} and Matthias Nahrendorf and Vasilis Ntziachristos and Ralph Weissleder",

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AU - Vinegoni, Claudio

AU - Razansky, Daniel

AU - Figueiredo, Jose Luiz

AU - Nahrendorf, Matthias

AU - Ntziachristos, Vasilis

AU - Weissleder, Ralph

PY - 2009/2/1

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N2 - We present a normalized Born approach for fluorescence optical projection tomography that takes into account tissue absorption properties. This approach can be particularly useful to study fluorochrome distribution within tissue. We use the algorithm to three-dimensionally reconstruct and characterize a fluorescein isothiocyanate containing absorptive phantom and an infarcted mouse heart previously injected with a fluorescent molecular probe.

AB - We present a normalized Born approach for fluorescence optical projection tomography that takes into account tissue absorption properties. This approach can be particularly useful to study fluorochrome distribution within tissue. We use the algorithm to three-dimensionally reconstruct and characterize a fluorescein isothiocyanate containing absorptive phantom and an infarcted mouse heart previously injected with a fluorescent molecular probe.

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SP - 319

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JO - Optics Letters

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Normalized Born ratio for fluorescence optical projection tomography

Abstract

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