Non-rigid image transformation for assessing changes in fluorescence imaging data of molecular activity in time-dependent geometries

Kostas Marias; Jorge Ripoll; Vasilis Ntziachristos; Stelios Orphanoudakis

Non-rigid image transformation for assessing changes in fluorescence imaging data of molecular activity in time-dependent geometries

Kostas Marias, Jorge Ripoll, Vasilis Ntziachristos, Stelios Orphanoudakis

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Scopus citations

Abstract

This paper presents an image processing framework for assessing molecular activity changes from fluorescent data in time-dependent geometries. The aim of our work is to provide the necessary tools in order to facilitate molecular imaging studies of small animals, where the basic problem is the time dependent geometry due to different measurement sessions or animal movement. Synthetic, fluorescence imaging data of molecular activity inside a mouse are produced numerically by moving the location of the fluorophore distribution and then randomly and non-linearly transforming the image. A method for aligning the temporal data and improving the accuracy of monitoring fluorophore distribution is presented.

Original language	English
Title of host publication	2004 2nd IEEE International Symposium on Biomedical Imaging
Subtitle of host publication	Macro to Nano
Pages	484-487
Number of pages	4
State	Published - 2004
Externally published	Yes
Event	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA, United States Duration: 15 Apr 2004 → 18 Apr 2004

Publication series

Name	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Volume	1

Conference

Conference	2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Country/Territory	United States
City	Arlington, VA
Period	15/04/04 → 18/04/04

Cite this

Marias, K., Ripoll, J., Ntziachristos, V., & Orphanoudakis, S. (2004). Non-rigid image transformation for assessing changes in fluorescence imaging data of molecular activity in time-dependent geometries. In 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (pp. 484-487). (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 1).

Marias, Kostas ; Ripoll, Jorge ; Ntziachristos, Vasilis et al. / Non-rigid image transformation for assessing changes in fluorescence imaging data of molecular activity in time-dependent geometries. 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004. pp. 484-487 (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano).

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title = "Non-rigid image transformation for assessing changes in fluorescence imaging data of molecular activity in time-dependent geometries",

abstract = "This paper presents an image processing framework for assessing molecular activity changes from fluorescent data in time-dependent geometries. The aim of our work is to provide the necessary tools in order to facilitate molecular imaging studies of small animals, where the basic problem is the time dependent geometry due to different measurement sessions or animal movement. Synthetic, fluorescence imaging data of molecular activity inside a mouse are produced numerically by moving the location of the fluorophore distribution and then randomly and non-linearly transforming the image. A method for aligning the temporal data and improving the accuracy of monitoring fluorophore distribution is presented.",

author = "Kostas Marias and Jorge Ripoll and Vasilis Ntziachristos and Stelios Orphanoudakis",

year = "2004",

language = "English",

isbn = "0780383885",

series = "2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano",

pages = "484--487",

booktitle = "2004 2nd IEEE International Symposium on Biomedical Imaging",

note = "2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano ; Conference date: 15-04-2004 Through 18-04-2004",

}

Marias, K, Ripoll, J, Ntziachristos, V & Orphanoudakis, S 2004, Non-rigid image transformation for assessing changes in fluorescence imaging data of molecular activity in time-dependent geometries. in 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, vol. 1, pp. 484-487, 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, Arlington, VA, United States, 15/04/04.

Non-rigid image transformation for assessing changes in fluorescence imaging data of molecular activity in time-dependent geometries. / Marias, Kostas; Ripoll, Jorge; Ntziachristos, Vasilis et al.
2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano. 2004. p. 484-487 (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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T1 - Non-rigid image transformation for assessing changes in fluorescence imaging data of molecular activity in time-dependent geometries

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AU - Ripoll, Jorge

AU - Ntziachristos, Vasilis

AU - Orphanoudakis, Stelios

PY - 2004

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N2 - This paper presents an image processing framework for assessing molecular activity changes from fluorescent data in time-dependent geometries. The aim of our work is to provide the necessary tools in order to facilitate molecular imaging studies of small animals, where the basic problem is the time dependent geometry due to different measurement sessions or animal movement. Synthetic, fluorescence imaging data of molecular activity inside a mouse are produced numerically by moving the location of the fluorophore distribution and then randomly and non-linearly transforming the image. A method for aligning the temporal data and improving the accuracy of monitoring fluorophore distribution is presented.

AB - This paper presents an image processing framework for assessing molecular activity changes from fluorescent data in time-dependent geometries. The aim of our work is to provide the necessary tools in order to facilitate molecular imaging studies of small animals, where the basic problem is the time dependent geometry due to different measurement sessions or animal movement. Synthetic, fluorescence imaging data of molecular activity inside a mouse are produced numerically by moving the location of the fluorophore distribution and then randomly and non-linearly transforming the image. A method for aligning the temporal data and improving the accuracy of monitoring fluorophore distribution is presented.

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M3 - Conference contribution

AN - SCOPUS:17144377136

SN - 0780383885

SN - 9780780383883

T3 - 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano

SP - 484

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BT - 2004 2nd IEEE International Symposium on Biomedical Imaging

T2 - 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano

Y2 - 15 April 2004 through 18 April 2004

ER -

Non-rigid image transformation for assessing changes in fluorescence imaging data of molecular activity in time-dependent geometries

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