No Magic Bullet: Genetic Diagnostics and Predictive Testing

Translated title of the contribution: No Magic Bullet: Genetic Diagnostics and Predictive Testing

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Abstract

The enormous increase in knowledge about the genetic basis of human diseases, combined with the rapid development of genetic techniques, has led to the possible use of genetic tests in medical diagnostics to a degree previously unknown. In addition, predictive genetic diagnostics has the aim of identifying hereditary disease risks in healthy individuals in order to take precautionary measures. However, the assessment of genetic findings is still subject to numerous problems. In particular, in the case of disease prediction, only probability statements can be made since endogenous and exogenous factors influence the penetrance and expressivity of genetically determined diseases.

Translated title of the contributionNo Magic Bullet: Genetic Diagnostics and Predictive Testing
Original languageEnglish
Pages (from-to)652-656
Number of pages5
JournalDeutsche Medizinische Wochenschrift
Volume142
Issue number9
DOIs
StatePublished - 1 May 2017

Keywords

  • German gene diagnostics act
  • genetic testing
  • predictive genetic diagnostics

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