New variant of the human metapneumovirus (HMPV) associated with an acute and severe exacerbation of asthma bronchiale

Oliver Schildgen; Tilman Geikowski; Thomas Glatzel; Arne Simon; Anja Wilkesmann; Michael Roggendorf; Sergei Viazov; Bertfried Matz

doi:10.1016/j.jcv.2004.06.007

New variant of the human metapneumovirus (HMPV) associated with an acute and severe exacerbation of asthma bronchiale

Oliver Schildgen, Tilman Geikowski, Thomas Glatzel, Arne Simon, Anja Wilkesmann, Michael Roggendorf, Sergei Viazov, Bertfried Matz

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Recently, an increasing number of studies demonstrated that the human metapneumovirus (HMPV) causes mild to severe respiratory infections in children and immunosuppressed adults, and may be a frequent but somewhat undervalued pathogen. Here, we report the detection of a new variant of HMPV that is not closely related to the HMPV strains described until now. The strain was detected in a 6.5-year-old girl with an acute and severe exacerbation of asthma bronchiale triggered by an infection with a newly detected HMPV variant. The presented data provide new information on genetic heterogeneity of HMPV and necessitate an optimization of diagnostic procedures for the detection of HMPV infection.

Original language	English
Pages (from-to)	283-288
Number of pages	6
Journal	Journal of Clinical Virology
Volume	31
Issue number	4
DOIs	https://doi.org/10.1016/j.jcv.2004.06.007
State	Published - Dec 2004
Externally published	Yes

Keywords

Asthma bronchiale
HMPV
New variant Bonn-01

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jcv.2004.06.007

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title = "New variant of the human metapneumovirus (HMPV) associated with an acute and severe exacerbation of asthma bronchiale",

abstract = "Recently, an increasing number of studies demonstrated that the human metapneumovirus (HMPV) causes mild to severe respiratory infections in children and immunosuppressed adults, and may be a frequent but somewhat undervalued pathogen. Here, we report the detection of a new variant of HMPV that is not closely related to the HMPV strains described until now. The strain was detected in a 6.5-year-old girl with an acute and severe exacerbation of asthma bronchiale triggered by an infection with a newly detected HMPV variant. The presented data provide new information on genetic heterogeneity of HMPV and necessitate an optimization of diagnostic procedures for the detection of HMPV infection.",

keywords = "Asthma bronchiale, HMPV, New variant Bonn-01",

author = "Oliver Schildgen and Tilman Geikowski and Thomas Glatzel and Arne Simon and Anja Wilkesmann and Michael Roggendorf and Sergei Viazov and Bertfried Matz",

note = "Funding Information: Sergei Viazov was supported by a Grant from the IFORES program of the Medical Faculty of the University of Essen.",

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doi = "10.1016/j.jcv.2004.06.007",

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T1 - New variant of the human metapneumovirus (HMPV) associated with an acute and severe exacerbation of asthma bronchiale

AU - Schildgen, Oliver

AU - Geikowski, Tilman

AU - Glatzel, Thomas

AU - Simon, Arne

AU - Wilkesmann, Anja

AU - Roggendorf, Michael

AU - Viazov, Sergei

AU - Matz, Bertfried

N1 - Funding Information: Sergei Viazov was supported by a Grant from the IFORES program of the Medical Faculty of the University of Essen.

PY - 2004/12

Y1 - 2004/12

N2 - Recently, an increasing number of studies demonstrated that the human metapneumovirus (HMPV) causes mild to severe respiratory infections in children and immunosuppressed adults, and may be a frequent but somewhat undervalued pathogen. Here, we report the detection of a new variant of HMPV that is not closely related to the HMPV strains described until now. The strain was detected in a 6.5-year-old girl with an acute and severe exacerbation of asthma bronchiale triggered by an infection with a newly detected HMPV variant. The presented data provide new information on genetic heterogeneity of HMPV and necessitate an optimization of diagnostic procedures for the detection of HMPV infection.

AB - Recently, an increasing number of studies demonstrated that the human metapneumovirus (HMPV) causes mild to severe respiratory infections in children and immunosuppressed adults, and may be a frequent but somewhat undervalued pathogen. Here, we report the detection of a new variant of HMPV that is not closely related to the HMPV strains described until now. The strain was detected in a 6.5-year-old girl with an acute and severe exacerbation of asthma bronchiale triggered by an infection with a newly detected HMPV variant. The presented data provide new information on genetic heterogeneity of HMPV and necessitate an optimization of diagnostic procedures for the detection of HMPV infection.

KW - Asthma bronchiale

KW - HMPV

KW - New variant Bonn-01

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JF - Journal of Clinical Virology

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ER -

New variant of the human metapneumovirus (HMPV) associated with an acute and severe exacerbation of asthma bronchiale

Abstract

Keywords

UN SDGs

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