Neuromuskuläre komplikationen nach allogener knochenmarktransplantation

Translated title of the contribution: Neuromuscular complications after allogeneic bone marrow transplantation

C. S. Padovan, P. Sostak, P. Reich, H. J. Kolb, W. Müller-Felber, A. Straube

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Neuromuscular syndromes following allogeneic bone marrow transplantation (BMT), although occasionally described, were not the focus of studies concerning neurologic complications following bone marrow transplantation. In this study, we summarize different polyneuropathy syndromes following BMT and report on patients with myasthenia gravis and inflammatory neuromuscular disorders such as myositis or fasciitis. Concerning the etiology of neuropathies, a neurotoxicity of immunosuppressants, a preexisting disorder due to the underlying disease as well as an association with graft-versus-host disease (GVHD) is discussed. GVHD-associated polyneuropathies as well as muscular complications have been found to occur during the early BMT phase, while myasthenia gravis is a late neurologic complication of GVHD.

Translated title of the contributionNeuromuscular complications after allogeneic bone marrow transplantation
Original languageGerman
Pages (from-to)159-166
Number of pages8
JournalNervenarzt
Volume74
Issue number2
DOIs
StatePublished - 1 Feb 2003
Externally publishedYes

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