Nerve-driven immunity: The effects of neurotransmitters on immune cells, functions and disease: CGRP

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

The peripheral nervous system may influence immune responses through the release of neuropeptides such as CGRP. Tissue concentrations of CGRP rapidly increase in response to infection and inflammation. This review will focus on the regulatory effects of CGRP on innate and adaptive immune responses and the role of CGRP in inflammatory disorders. Current concepts for the molecular basis of these effects are discussed. It is proposed that CGRP mediates a potent peptidergic antiinflammatory pathway.

Original languageEnglish
Title of host publicationNerve-Driven Immunity
Subtitle of host publicationNeurotransmitters and Neuropeptides in the Immune System
PublisherSpringer-Verlag Wien
Pages289-306
Number of pages18
ISBN (Electronic)9783709108888
ISBN (Print)9783709108871
DOIs
StatePublished - 1 Jan 2012
Externally publishedYes

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