Natural history of type 1 diabetes

Peter Achenbach; Ezio Bonifacio; Kerstin Koczwara; Anette G. Ziegler

doi:10.2337/diabetes.54.suppl_2.S25

Natural history of type 1 diabetes

Peter Achenbach
, Ezio Bonifacio
, Kerstin Koczwara
, Anette G. Ziegler

Institute for Diabetes Research

Research output: Contribution to journal › Review article › peer-review

214 Scopus citations

Abstract

The natural history of autoimmune type 1 diabetes in children is associated with the appearance of islet autoantibodies early in life, which is influenced by genetic and environmental factors. Once islet autoantibodies have developed, the progression to diabetes in antibody-positive individuals is determined by the age of antibody appearance and by the magnitude of the autoimmunity, in turn related to the age of the subject. Characteristics that describe the magnitude of the autoimmunity can stage progression to type 1 diabetes in islet autoantibody-positive subjects regardless of genetic background or age.

Original language	English
Pages (from-to)	S25-S31
Journal	Diabetes
Volume	54
Issue number	SUPPL. 2
DOIs	https://doi.org/10.2337/diabetes.54.suppl_2.S25
State	Published - Dec 2005
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.2337/diabetes.54.suppl_2.S25

Cite this

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abstract = "The natural history of autoimmune type 1 diabetes in children is associated with the appearance of islet autoantibodies early in life, which is influenced by genetic and environmental factors. Once islet autoantibodies have developed, the progression to diabetes in antibody-positive individuals is determined by the age of antibody appearance and by the magnitude of the autoimmunity, in turn related to the age of the subject. Characteristics that describe the magnitude of the autoimmunity can stage progression to type 1 diabetes in islet autoantibody-positive subjects regardless of genetic background or age.",

author = "Peter Achenbach and Ezio Bonifacio and Kerstin Koczwara and Ziegler, \{Anette G.\}",

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AU - Achenbach, Peter

AU - Bonifacio, Ezio

AU - Koczwara, Kerstin

AU - Ziegler, Anette G.

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Y1 - 2005/12

N2 - The natural history of autoimmune type 1 diabetes in children is associated with the appearance of islet autoantibodies early in life, which is influenced by genetic and environmental factors. Once islet autoantibodies have developed, the progression to diabetes in antibody-positive individuals is determined by the age of antibody appearance and by the magnitude of the autoimmunity, in turn related to the age of the subject. Characteristics that describe the magnitude of the autoimmunity can stage progression to type 1 diabetes in islet autoantibody-positive subjects regardless of genetic background or age.

AB - The natural history of autoimmune type 1 diabetes in children is associated with the appearance of islet autoantibodies early in life, which is influenced by genetic and environmental factors. Once islet autoantibodies have developed, the progression to diabetes in antibody-positive individuals is determined by the age of antibody appearance and by the magnitude of the autoimmunity, in turn related to the age of the subject. Characteristics that describe the magnitude of the autoimmunity can stage progression to type 1 diabetes in islet autoantibody-positive subjects regardless of genetic background or age.

UR - https://www.scopus.com/pages/publications/33644761987

U2 - 10.2337/diabetes.54.suppl_2.S25

DO - 10.2337/diabetes.54.suppl_2.S25

M3 - Review article

C2 - 16306336

AN - SCOPUS:33644761987

SN - 0012-1797

VL - 54

SP - S25-S31

JO - Diabetes

JF - Diabetes

IS - SUPPL. 2

ER -

Natural history of type 1 diabetes

Abstract

UN SDGs

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