Nanopore translocation and force spectroscopy experiments in microemulsion droplets

Stephan Renner, Sandra Geltinger, Friedrich C. Simmel

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Nanopore translocation experiments are performed using a novel setup based on microemulsion droplets. This scales down the required analyte volume to only a few picoliters and provides very stable membranes for single-molecule nanopore experiments. Using this setup, the stability of hairpin DNA and G-quadruplex DNA Is studied by nanopore force spectroscopy.

Original languageEnglish
Pages (from-to)190-194
Number of pages5
JournalSmall
Volume6
Issue number2
DOIs
StatePublished - 18 Jan 2010

Keywords

  • Aptamers
  • Dna structures
  • Hemolysin
  • Mlcroemulsions nanopores

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