Nachweis und Vorkommen von Mykophenolsäure und Citrinin in Rotwein

Translated title of the contribution: Detection and occurrence of mycophenolic acid and citrinin in red wine

K. Meyer, T. Müller, R. Dietrich, E. Märtlbauer, J. Bauer

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Due to infections with moulds already in the vineyards, the formation of mycotoxins is possible under certain circumstances during the process of red wine making. At this, metabolites of Penicillium spp. are of major importance, as this species are to be found frequently on grapes. Beside the nephrotoxic citrinin, which is often co-occurring with ochratoxin A, the occurrence of myco-phenolic acid (MPA), a substance of immunosuppressive action, was investigated since it is formed by a great number of Penicillium-species. The detection of these compounds was carried out by means of ELISA and LC-MS. As testing material 44 red wine samples of different provenience and vintages were used. Mycophenolic acid could be detected in 91 % of the samples. The maximum content amounted to 130 ng/ml, yet most of the samples resulted in much lower concentrations of between 3 and 20 ng/ml. The extent of contamination seems to depend rather on the origin of the wine than on the vintage. In particular samples from Southern Europe were most contaminated. This could be due to different practises in wine-making. Citrinin was not detectable in any sample (< 0,2 ng/ml). Regarding the detected concentrations of MPA and citrinin, there is probably no concern for consumers' health. However, the degree of contamination of wine with MPA may well serve as an indicator for hygiene in production.

Translated title of the contributionDetection and occurrence of mycophenolic acid and citrinin in red wine
Original languageGerman
Pages (from-to)160-164
Number of pages5
JournalMycotoxin Research
Issue number2 SUPPL.
StatePublished - Jun 2001
Externally publishedYes


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