Myeloid sarcoma of the heart—A clinicopathological correlation

Kristijan Skok; Martin Zacharias; Nicolas Verheyen; Stefan Hatzl; Laura Scholz; Cord Langner; Gerald Hoefler; Fotini Rosi Vagena

doi:10.1007/s00508-024-02478-3

Myeloid sarcoma of the heart—A clinicopathological correlation

Kristijan Skok, Martin Zacharias, Nicolas Verheyen, Stefan Hatzl, Laura Scholz, Cord Langner, Gerald Hoefler, Fotini Rosi Vagena

Medical University of Graz

Research output: Contribution to journal › Article › peer-review

Abstract

A 63-year-old woman with a history of acute myeloid leukemia followed by stem cell transplantation presented with acute heart failure. Transthoracic echocardiography revealed a preserved left ventricular ejection fraction with severe ventricular hypertrophy and signs of elevated filling pressures indicating infiltrative cardiomyopathy. She died from cardiac arrest due to cardiogenic shock. The autopsy revealed an enlarged heart with a fish-flesh appearance. Here, we describe a rare case of a myeloid sarcoma of the heart.

Original language	English
Pages (from-to)	251-254
Number of pages	4
Journal	Wiener Klinische Wochenschrift
Volume	137
Issue number	7
DOIs	https://doi.org/10.1007/s00508-024-02478-3
State	Published - Apr 2025
Externally published	Yes

Keywords

Acute myeloid leukemia
Cardiomyopathy
Clinical pathology conference
Rare diseases
TP53

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10.1007/s00508-024-02478-3

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title = "Myeloid sarcoma of the heart—A clinicopathological correlation",

abstract = "A 63-year-old woman with a history of acute myeloid leukemia followed by stem cell transplantation presented with acute heart failure. Transthoracic echocardiography revealed a preserved left ventricular ejection fraction with severe ventricular hypertrophy and signs of elevated filling pressures indicating infiltrative cardiomyopathy. She died from cardiac arrest due to cardiogenic shock. The autopsy revealed an enlarged heart with a fish-flesh appearance. Here, we describe a rare case of a myeloid sarcoma of the heart.",

keywords = "Acute myeloid leukemia, Cardiomyopathy, Clinical pathology conference, Rare diseases, TP53",

author = "Kristijan Skok and Martin Zacharias and Nicolas Verheyen and Stefan Hatzl and Laura Scholz and Cord Langner and Gerald Hoefler and Vagena, {Fotini Rosi}",

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AU - Skok, Kristijan

AU - Zacharias, Martin

AU - Verheyen, Nicolas

AU - Hatzl, Stefan

AU - Scholz, Laura

AU - Langner, Cord

AU - Hoefler, Gerald

AU - Vagena, Fotini Rosi

N1 - Publisher Copyright: © The Author(s) 2024.

PY - 2025/4

Y1 - 2025/4

N2 - A 63-year-old woman with a history of acute myeloid leukemia followed by stem cell transplantation presented with acute heart failure. Transthoracic echocardiography revealed a preserved left ventricular ejection fraction with severe ventricular hypertrophy and signs of elevated filling pressures indicating infiltrative cardiomyopathy. She died from cardiac arrest due to cardiogenic shock. The autopsy revealed an enlarged heart with a fish-flesh appearance. Here, we describe a rare case of a myeloid sarcoma of the heart.

AB - A 63-year-old woman with a history of acute myeloid leukemia followed by stem cell transplantation presented with acute heart failure. Transthoracic echocardiography revealed a preserved left ventricular ejection fraction with severe ventricular hypertrophy and signs of elevated filling pressures indicating infiltrative cardiomyopathy. She died from cardiac arrest due to cardiogenic shock. The autopsy revealed an enlarged heart with a fish-flesh appearance. Here, we describe a rare case of a myeloid sarcoma of the heart.

KW - Acute myeloid leukemia

KW - Cardiomyopathy

KW - Clinical pathology conference

KW - Rare diseases

KW - TP53

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M3 - Article

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SP - 251

EP - 254

JO - Wiener Klinische Wochenschrift

JF - Wiener Klinische Wochenschrift

IS - 7

ER -

Myeloid sarcoma of the heart—A clinicopathological correlation

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Keywords

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