Abstract
The aim of the treatment of invasive bladder cancer with radical cystectomy and subsequent urinary diversion is to combine a safe oncological procedure with a satisfactory quality of life. Radical cystectomy is the treatment of choice for all patients with recurrent or multifocal high-grade T1 bladder cancer, T1 tumors at high risk of progression, failure of bacillus Calmette-Guérin (BCG) treatment and muscle-invasive bladder cancer. Radical cystectomy offers excellent recurrence-free and cancer-specific survival rates as well as local tumor control in patients with organ-confined and node-negative diseases. Tumor control in non-organ-confined tumors is still satisfactory with long-term relapse-free survial rates of about 50%. Nerve-sparing cystectomy is of importance for the lower urinary tract function, including continence rates after orthotopic urinary diversion and for sexual function in males and females. Orthotopic urinary reconstruction using a neobladder achieves good continence rates. Overall quality of life after radical cystectomy remains good in most patients irrespective of urinary diversion type.
| Translated title of the contribution | Muscle-invasive bladder cancer. Function-preserving cystectomy and urinary diversion in 2012 |
|---|---|
| Original language | German |
| Pages (from-to) | 977-984 |
| Number of pages | 8 |
| Journal | Onkologe |
| Volume | 18 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 2012 |
