Multispectral Optoacoustic Imaging of Peripheral Nerve Vascularization and Morphology

Dominik Jüstel, Hedwig Irl, Florian Hinterwimmer, Christoph Dehner, Walter Simson, Nassir Navab, Gerhard Schneider, Vasilis Ntziachristos

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


Imaging peripheral nerve morphology, function, and vascular supply is important in clinical medicine and research. In this work, we evaluate the imaging capabilities of multispectral optoacoustic tomography (MSOT) for peripheral nerves. We demonstrate how recent advances in MSOT data processing combined with data-driven unmixing overcome adverse effects of measurement noise and light fluence attenuation and provide detailed insights into the vasa nervorum and the internal structure of peripheral nerves.

Original languageEnglish
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2024
EditorsAlexander A. Oraevsky, Lihong V. Wang
ISBN (Electronic)9781510669437
StatePublished - 2024
EventPhotons Plus Ultrasound: Imaging and Sensing 2024 - San Francisco, United States
Duration: 28 Jan 202431 Jan 2024

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferencePhotons Plus Ultrasound: Imaging and Sensing 2024
Country/TerritoryUnited States
CitySan Francisco


  • Multispectral optoacoustic tomography
  • data-driven unmixing
  • peripheral nerves


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